Results 181 to 190 of about 897,105 (339)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Subsistence fishing patterns near food deserts. [PDF]

open access: yesProc Natl Acad Sci U S A
Swinea SH   +5 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Assessing fish welfare in small-scale commercial fixed-net fisheries off the Southern Portuguese coast. [PDF]

open access: yesPLoS One
Samel V   +7 more
europepmc   +1 more source

Summary of the seven Marine Protected Areas (MPAs) sampled using stereo-BRUVs in the oceanic island and coastal biogeographic subprovinces of the Tropical Eastern Pacific (TEP). Multiple use areas are not fully protected including designated zones for science, tourism or fishing.

open access: green
Simon J. McKinley (22289587)   +10 more
openalex   +1 more source

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