The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
Stock Status of Noncommercial Fish Species in Aras Dam Reservoir: Mismanagement Endangers Sustainable Fisheries. [PDF]
Haghi Vayghan A, Ghanbarzadeh M, Su NJ.
europepmc +1 more source
Unutilized fishes and their relation to the fishing industries / [by Irving A. Field]
Irving Angell Field
openalex +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Adjusting the management of the Antarctic krill fishery to meet the challenges of the 21st century. [PDF]
Meyer B +18 more
europepmc +1 more source
Fish tropomyosin and fish nucleotropomyosin [PDF]
openaire +3 more sources
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Temporal Variation and Assembly Process of Fish Communities in a Typical Canalized River After the 10-Year Fishing Ban. [PDF]
Qin Q +6 more
europepmc +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Differences in habitat variability of the northwestern Indian Ocean's Sthenoteuthis oualaniensis in response to ENSO events. [PDF]
Ding P, Zou B, Xu H, Tang W, Wu F.
europepmc +1 more source

