CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Linking Biological Parameters to Fishery Management: Stock Assessment of Green Tiger Prawn, <i>Penaeus semisulcatus</i> De Haan, 1844 Along the Red Sea Coast of Saudi Arabia. [PDF]
Tıraşın EM +8 more
europepmc +1 more source
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Biodiversity and Conservation of Marine Mollusks in the Indo-Pacific Convergence Zone. [PDF]
Lai X +6 more
europepmc +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Fish hatching, and fish catching
Robert Barnwell Roosevelt, Seth Green
openaire +3 more sources
Mapping regenerative value network configurations of marine plastics in the global commons. [PDF]
Mead T, Dijkstra H, Godfrey K.
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Low-Level Light Therapy as a Potential Adjunctive Approach in Mucus Fishing Syndrome: Report of Two Clinical Cases. [PDF]
Mancini A +11 more
europepmc +1 more source
Statistical Study on Small Passenger, Fishing and Cargo Vessels in the World
Javad A. Mehr, Seif, AH Hesabi
openalex

