Results 61 to 70 of about 23,414 (198)
Surfe: uma revisão sistemática
Introdução: Apesar da maior popularidade do surf e da evolução no desenvolvimento de equipamentos esportivos para a modalidade, a literatura científica especializada relata que pouco se sabe sobre os fatores relacionados ao treinamento e performance ...
Luiz Fernando Novack, Raul Osiecki
doaj
MORPHOLOGICAL RESPONSE OF THE RUMINAL AND OMASAL MUCOSAE TO THE VARIATION IN DIET ENERGY
The absorption capacity of the rumen responds positively to direct and indirect stimulation by VFA; there is also evidence that the wall of the omasum also responds to these stimuli.
Ronaldo Francisco Lima +5 more
doaj +1 more source
INFLUÊNCIA DOS HORMÔNIOS SEXUAIS NA REGULAÇÃO FISIOLÓGICA DA RESPIRAÇÃO: UMA REVISÃO DE LITERATURA
O Sistema respiratório é responsável por oxigenar todo o sangue que esteja pobre em oxigênio (O2), e remover do nosso sangue o gás carbônico (CO2). Mesmo que não haja regulação dos hormônios sexuais referentes ao processo de respiração, a literatura ...
Weslley Barbosa Sales +1 more
doaj +1 more source
We demonstrated that progerin induces the formation of autophagosomes but impairs their maturation and subsequent fusion with lysosomes. Progerin impedes proper autophagy flux, thus preventing its own autophagic degradation. Selinexor treatment improved both autophagosome maturation and autophagosome‐lysosome fusion, which ultimately led to effective ...
Ian García‐Aguirre +18 more
wiley +1 more source
Celebrating Rodolfo Margaria and applied physiology in Milan
Experimental Physiology, EarlyView.
Alberto E. Minetti +2 more
wiley +1 more source
Targeting RANKL Prevents Bone Loss, Improves Muscle Function and Extends Lifespan in Progeroid Mice
Targeting of RANKL by genetic and pharmacological approaches ameliorates key features of the progeroid phenotype in Zmpste24−/− mice. RANKL intervention restores bone mass, improves muscle phenotype, and extends survival. These findings support further exploration of RANKL‐targeted therapies for Hutchinson‐Gilford progeria syndrome.
Sandra Freitas‐Rodríguez +11 more
wiley +1 more source
O objetivo deste estudo foi determinar o efeito da temperatura (0 a 45°C), pH (4 a 10) e concentração de NaCl (1 a 10%) sobre o crescimento de Acidovorax avenae subsp. citrulli (Aac). Quatro estirpes de Aac foram cultivadas em meio de cultura líquido
Márcia Tanajura Cavalcanti +3 more
doaj +1 more source
Pharmacological Inhibition of Cav2.2 Channels by Recombinant Phα1β Toxin (CTK01512‐2)
The recombinant Phα1β toxin (CTK01512‐2) partially and reversibly inhibits Cav2.2 calcium channels in HEK‐293 cells. CTK01512‐2 displays dose‐dependent inhibition of N‐type calcium currents, with an IC50 of 3.94 nM. In vivo, CTK01512‐2 effectively reduces mechanical allodynia in a neuropathic pain model, confirming its antinociceptive activity ...
Natália Virtude Carobin +5 more
wiley +1 more source
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda +5 more
wiley +1 more source
ABSTRACT Minimal residual disease (MRD) has emerged as a central biomarker in hematologic malignancies, enabling highly sensitive detection of tumor persistence beyond conventional morphologic assessment and serving as an increasingly important surrogate endpoint in clinical trials.
Santino Caserta +14 more
wiley +1 more source

