Annals of Neurology, EarlyView.Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian +9 more
wiley +1 more source
Constraints on the evolution of Taranaki Fault from thermochronology and basin analysis: Implications for the Taranaki Fault play [PDF]
, 2004 Taranaki Fault is the major structure defining the eastern margin of Taranaki Basin and marks the juxtaposition of basement with the Late Cretaceous-Paleogene succession in the basin.
Hansen, Rochelle J. +7 more
core +1 more source
Exhumation, crustal deformation, and thermal structure of the Nepal Himalaya derived from the inversion of thermochronological and thermobarometric data and modeling of the topography [PDF]
, 2010 Two end‐member kinematic models of crustal shortening across the Himalaya are currently debated: one assumes localized thrusting along a single major thrust fault, the Main Himalayan Thrust (MHT) with nonuniform underplating due to duplexing, and the ...
Avouac, Jean‐Philippe +10 more
core +5 more sources
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Phanerozoic Large Igneous Province, Petroleum System, and Source Rock Links
Geophysical Monograph Series, Page 191-228., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Steven C. Bergman +2 more
wiley +1 more source
Ages on weathered Plio-Pleistocene tephra sequences, western North Island, New Zealand [PDF]
, 2001 Using the zircon fission-track method, we have obtained five ages on members of two strongly-weathered silicic, Pliocene-Pleistocene tephra sequences, the Kauroa and Hamilton Ash formations, in western North Island, New Zealand.
Briggs, Roger M. +5 more
core +1 more source
Marine tephrochronology: a personal perspective [PDF]
, 2014 This special volume on marine tephrochronology is remarkable, and timely, because it marks a concerted step towards what might be informally termed ‘phase 3’ of a revolution in Quaternary geosciences that began around 40 years ago.
Lowe, David J.
core +2 more sources
Terrestrial, Atmospheric and Oceanic Sciences, 2013 This study used a new set of zircon and apatite fission track ages to quantitatively document the tectonic evolution and cooling histories of the Qiangtang block of the central Tibetan Plateau.
Chunyan Song +3 more
doaj +1 more source
Geologica Carpathica, 2014 The Tatra Mts area, located in the northernmost part of Central Western Carpathians on the border between Slovakia and Poland, underwent a complex Alpine tectonic evolution.
Králiková Silvia +6 more
doaj +1 more source
Sedimentation record in the Konkan-Kerala Basin: implications for the evolution of the Western Ghats and the Western Indian passive margin [PDF]
, 2007 The Konkan and Kerala Basins constitute a major depocentre for sediment from the onshore hinterland of Western India and as such provide a valuable record of the timing and magnitude of Cenozoic denudation along the continental margin.
Allen P.A. +43 more
core +1 more source