Results 71 to 80 of about 49,074 (273)

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Interpreting and reporting fission-track chronological data

Geological Society of America Bulletin
Fission-track dating is based on the analysis of tracks—linear damage trails—produced by the spontaneous fission of 238U in a range of natural accessory minerals and glasses.
B. P. Kohn, R. Ketcham, Pieter Vermeesch, Samuel C. Boone, N. Hasebe, David Chew, M. Bernet, Ling Chung, M. Danišík, A. Gleadow, E. Sobel   +10 more
semanticscholar   +1 more source

Fission track dating of apatites from Coronation Island [PDF]

, 1981
Fission track ages were obtained from two apatite samples from Coronation Island near the Antarctic Peninsula. These ages, 177 and 188m.y. (λ_F=6.85x10^-17yr^-1), represent the last time the rocks cooled below approximately 100°C and probably reflect ...
Palmieri, Michael Herman
core  

Exhumation history of the Higher Himalayan Crystalline along Dhauliganga-Goriganga river valleys, NW India: new constraints from fission track analysis [PDF]

, 2009
New apatite and zircon fission track data collected from two transects along the Dhauliganga and Goriganga rivers in the NW Himalaya document exhumation of the Higher Himalayan Crystalline units. Despite sharing the same structural configuration and rock
A. Carter, Ahmad, Beaumont, Blythe, Bojar, Bollinger, Bookhagen, Bouchez, Brandon, Braun, Burbank, Burchfiel, Burg, Davidson, Dezes, Ehlers, Foster, Galbraith, Gansser, Garzanti, Grujic, Gururajan, Heim, Herren, Hodges, Hodges, Hubbard, Huntington, Hurford, Hurford, Jain, Jain, Jain, Jain, Lal, Leech, Mancktelow, Metcalfe, Molnar, Patel, Patriat, Paul, R. C. Patel, Rao, Ray, Rowley, Roy, Schlup, Searle, Searle, Seitz, Singh, Sorkhabi, Srivastava, Stern, Stüwe, Thakur, Thiede, Thiede, Thiede, Valdiya, Vannay, Whipp, Whipp, Whipple, Whipple, Yin   +66 more
core   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Extremely low long‐term erosion rates around the Gamburtsev Mountains in interior East Antarctica [PDF]

, 2010
The high elevation and rugged relief (>3 km) of the Gamburtsev Subglacial Mountains (GSM) have long been considered enigmatic. Orogenesis normally occurs near plate boundaries, not cratonic interiors, and large‐scale tectonic activity last occurred in ...
Cox, S. E., Hemming, S. R., Reiners, P. W., Thomson, S. N., van de Flierdt, T.   +4 more
core   +2 more sources

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

The FEBS Journal, EarlyView.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma, Mark T. S. Williams   +1 more
wiley   +1 more source

Exhumation of the Sierra de Cameros (Iberian Range, Spain): constraints from low-temperature thermochronology [PDF]

, 2008
We present new fission-track and (U–Th)/He data from apatite and zircon in order to reconstruct the exhumation of the Sierra de Cameros, in the northwestern part of Iberian Range, Spain. Zircon fission-track ages from samples from the depocentre of the
Casquet, F. M. Stuart, Foeken, Gil-Imaz, Gil-Imaz, Gil-Imaz, Goldberg, Guiraud, Hurford, Ketcham, L. Barbero, Mas, Mas, Mata, Muñoz, P. Del Río, Schudack, Tischer   +17 more
core   +2 more sources

Polyphase Exhumation of the East Kunlun Orogenic Belt: Evidence from Modern River Detrital Zircon and Apatite Fission Track Dating [PDF]

Lithosphere
The East Kunlun Orogenic Belt (E-KOB) stands out as one of the most prominent basin-mountain geomorphic features in the northern interior of the Tibetan Plateau. It records a series of accretion-collision events from the Mesozoic to the Cenozoic.
Yuxiong Ma, Zhao Yang, Dengfeng He, Xiaohui Shi, Bo Zhou, Jiali You, Dali Ju, Yunpeng Dong   +7 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source