Results 171 to 180 of about 253,060 (248)

Innovation in the imaging of perianal fistula: a step towards personalised medicine [PDF]

open access: gold, 2018
Kapil Sahnan   +9 more
openalex   +1 more source

Medicaid Coverage and Utilization for Novel Therapies for Chronic Rhinosinusitis With Nasal Polyposis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
Key Points Most state Medicaid programs granted omalizumab (91.4%) and dupilumab (59.5%) preferred drug status. Omalizumab was the most commonly prescribed therapy among Medicaid patients between 2015 and2024.
Eric R. Ramos   +7 more
wiley   +1 more source

Overexpression of mitofusin 2 ameliorates inflammation and oxidative stress in lipopolysaccharide‐induced mastitis model by regulating phosphofurin acidic cluster sorting protein 2

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The interaction between mitofusin 2 (MFN2) and phosphofurin acidic cluster sorting protein 2 regulates the formation of mitochondria‐associated endoplasmic reticulum membranes (MAM). Overexpression of MFN2 can promote the formation of MAMs and inhibit inflammation and oxidative stress response in mammary epithelial cells.
Xiechen Zhou   +7 more
wiley   +1 more source

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai   +7 more
wiley   +1 more source

Building a humane scientific future: Second Asia Laboratory Animal Day

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Frontiers in Laboratory Animal Handling and Experimental Design: Bridging Ethics and Excellence Theme: Good Science with Good Care Ethical Framework: CCSEA & IAEC oversight | 3Rs (Replacement, Reduction, Refinement) | Transparent documentation Animal Handling & Anatomy: Mice • Rats • Rabbits • Guinea pigs Gentle restraint • Anatomical landmarks ...
Vijay Pal Singh   +3 more
wiley   +1 more source

Is pneumonectomy still relevant for non-small cell lung cancer? Long-term overall survival from a 15-year experience. [PDF]

open access: yesCan J Surg
Hache PL   +8 more
europepmc   +1 more source

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

open access: yesAnnals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek   +7 more
wiley   +1 more source

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