Animal Models and Experimental Medicine, EarlyView.In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang +6 more
wiley +1 more source
Diosgenin ameliorates silica‐induced tuberculosis in rats
Animal Models and Experimental Medicine, EarlyView.Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu +5 more
wiley +1 more source
Entero-vascular fistula following radiotherapy in a patient with recurrent cervical cancer post-pelvic exenteration: a case report. [PDF]
BMC Womens HealthHwang IS, Hur SY.
europepmc +1 more source
Sheep femoral artery occlusion is well tolerated and does not result in ischemia
Animal Models and Experimental Medicine, EarlyView.Left femoral artery occlusion (yellow arrows) can be seen shortly after the lateral femoral circumflex artery origin, with distal arterial reconstitution. Sheep with femoral artery occlusion showed no change in pain scores nor mobility, thus making them an appropriate model for novel small diameter femoral artery graft studies. Abstract Objective Sheep
Timothy Shiraev +10 more
wiley +1 more source
Detection and significance of AKT/mTOR/P70S6K signaling pathway in gastrointestinal stromal tumors
Asian Journal of Surgery, 2023 Meng Wang, Xiao Gang Zhong
doaj
New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond
Annals of Neurology, EarlyView.The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr. +2 more
wiley +1 more source
Ultrasound assessment of low type intersphincteric perianal fistulas in Yemen. [PDF]
Sci RepAlshoabi SA +11 more
europepmc +1 more source
ANATOMICAL EXAMINATION OF SIX NEW CASES OF SUBCONJUNCTIVAL FISTULA SCARS FROM FIVE MONTHS TO SIX YEARS AFTER SUCCESSFUL IRIDENCLEISIS OR LIMBAL SCLERECTOMIES IN CHRONIC GLAUCOMA [PDF]
, 1922 S. Holth
openalex +1 more source
Cholecystoduodenal fistula with migrated gallstone leading to gastric outlet obstruction : Bouveret's syndrome [PDF]
, 2017 De Backer, Adelard I +2 more
core +2 more sources