Results 31 to 40 of about 253,060 (248)

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Precise Control of Drug Release in Machine Learning‐Designed Antibody‐Eluting Implants for Postoperative Scarring Inhibition in Glaucoma

Advanced Healthcare Materials, EarlyView.
We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin, Wenbing Jiang, Kai Xin Thong, Zeynep Ulker, Brihitejas Patel, Cynthia Yu‐Wai‐Man   +5 more
wiley   +1 more source

Clinical Use of S53P4 Bioactive Glass in the Treatment of Bone Defects and Infected Bone: A Systematic Review of the Quality of Clinical Outcomes and A Grade Assessment

Advanced Healthcare Materials, EarlyView.
Bioactive glass (BAG) S53P4 is a synthetic bone substitute. Clinically it has been used in the treatment of benign bone tumor surgery, in spine surgery, in trauma surgery, in frontal sinus surgery, in diabetic foot osteomyelitis surgery, in mastoid surgery, in oral and maxillofacial surgery in more than 4000 patients, with excellent clinical long‐term ...
Sebastian CE Lindfors, Chris JJ Arts, Nina C Lindfors   +2 more
wiley   +1 more source

AI-Generated Patient-Friendly MRI Fistula Summaries: A Pilot Randomised Study

Journal of Imaging
Perianal fistulising Crohn’s disease (pfCD) affects 1 in 5 Crohn’s patients and requires frequent MRI monitoring. Standard radiology reports are written for clinicians using technical language often inaccessible to patients, which can cause anxiety and ...
Easan Anand, Itai Ghersin, Gita Lingam, Theo Pelly, Daniel Singer, Chris Tomlinson, Robin E. J. Munro, Rachel Capstick, Anna Antoniou, Ailsa L. Hart, Phil Tozer, Kapil Sahnan, Phillip Lung   +12 more
doaj   +1 more source

Pyopneumothorax with bronchopleural fistula due to pulmonary infection caused by Porphyromonas gingivalis in a patient with periodontitis

The Clinical Respiratory Journal, 2023
Pyopneumothorax with bronchopleural fistula is a rare complication of lung infection. We herein report a case of pyopneumothorax with bronchopleural fistula caused by Porphyromonas gingivalis infection, a common pathogenic pathogen of periodontitis, in a
Jun Sha, Jie Shao, Sheng Lu, Wei Yao, Yimai Deng, Jie Chen, Jianfeng Zhang, Yufeng Feng   +7 more
doaj   +1 more source

Mesenchymal Stem/Stromal Cell Therapy Is More Cost-Effective Than Fecal Diversion for Treatment of Perianal Crohn’s Disease Fistulas [PDF]

, 2022
Sheeva Johnson, Jeffrey S. Hoch, Wissam J. Halabi, Jeffrey Ko, Jan A. Nolta, Maneesh Dave   +5 more
openalex   +1 more source

A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions

Advanced Healthcare Materials, EarlyView.
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan, Partho Protim Adhikary, Dana Wörz, Sarah Hedtrich   +3 more
wiley   +1 more source

Mainz II urinary diversion in low-resource settings: patient outcomes in women with irreparable fistula in MalawiAJOG MFM at a Glance

AJOG Global Reports
BACKGROUND: Obstructed labor leading to a vesicovaginal fistula remains a devastating outcome of childbirth in low-resource countries. Women with an irreparable vesicovaginal fistula may be candidates for a urinary diversion, such as the Mainz II ...
Tulsi D. Patel, MD, Ennet B. Chipungu, MBBS, Jennifer M. Draganchuk, MD, Chisomo Chalamanda, DCM, Jeffrey P. Wilkinson, MD   +4 more
doaj   +1 more source

Congenital anterior urethrocutaneous fistula: Two case reports and review of literature

Urology Annals, 2014
Congenital anterior urethrocutaneous fistula (CAUF) of the male urethra is a rare anomaly. CAUF can be defined as a urethral fistula in which the urethra and external urethral meatus are intact, typically with intact prepuce and no history of any penile ...
Hamdan H Alhazmi
doaj   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source