Results 71 to 80 of about 226,725 (314)

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

AI-Generated Patient-Friendly MRI Fistula Summaries: A Pilot Randomised Study

Journal of Imaging
Perianal fistulising Crohn’s disease (pfCD) affects 1 in 5 Crohn’s patients and requires frequent MRI monitoring. Standard radiology reports are written for clinicians using technical language often inaccessible to patients, which can cause anxiety and ...
Easan Anand, Itai Ghersin, Gita Lingam, Theo Pelly, Daniel Singer, Chris Tomlinson, Robin E. J. Munro, Rachel Capstick, Anna Antoniou, Ailsa L. Hart, Phil Tozer, Kapil Sahnan, Phillip Lung   +12 more
doaj   +1 more source

Successful Treatment of Bronchoesophageal Fistula with Esophageal and Bronchial Stenting

, 2012
Bronchoesophageal fistula is reported in 5-10% of patients with esophageal cancer. In most of these cases, the insertion of a single stent , either a tracheobronchial or an esophageal stent, is sufficient to seal off the fistula. In this case we describe
王正一;周建宏;王秀伯;陳晉興;李佩玲, WANG, CHENG-YI;CHOU, CHIEN-HONG;WANG, HSIU-PO;CHEN, JIN-SHING;LEE, PEI-LING   +1 more
core   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Pyopneumothorax with bronchopleural fistula due to pulmonary infection caused by Porphyromonas gingivalis in a patient with periodontitis

The Clinical Respiratory Journal, 2023
Pyopneumothorax with bronchopleural fistula is a rare complication of lung infection. We herein report a case of pyopneumothorax with bronchopleural fistula caused by Porphyromonas gingivalis infection, a common pathogenic pathogen of periodontitis, in a
Jun Sha, Jie Shao, Sheng Lu, Wei Yao, Yimai Deng, Jie Chen, Jianfeng Zhang, Yufeng Feng   +7 more
doaj   +1 more source

Life-threatening Arterioureteral Fistula Between Iliac Vessel and Ureteral Stump: A Case Report

, 2022
Arterioureteral fistulas (AUFs) are a rare but life-threatening condition that cause massive hematuria. Radiation treatments, pelvic surgeries and chronic permanent ureteral stent use due to pelvic malignancies have been identified as the most important ...
Ahmet Ergin Çapar, Yusuf Özlem İlbey, Mert Hamza Özbilen, Erdem Kısa   +3 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Mainz II urinary diversion in low-resource settings: patient outcomes in women with irreparable fistula in MalawiAJOG MFM at a Glance

AJOG Global Reports
BACKGROUND: Obstructed labor leading to a vesicovaginal fistula remains a devastating outcome of childbirth in low-resource countries. Women with an irreparable vesicovaginal fistula may be candidates for a urinary diversion, such as the Mainz II ...
Tulsi D. Patel, MD, Ennet B. Chipungu, MBBS, Jennifer M. Draganchuk, MD, Chisomo Chalamanda, DCM, Jeffrey P. Wilkinson, MD   +4 more
doaj   +1 more source

Congenital anterior urethrocutaneous fistula: Two case reports and review of literature

Urology Annals, 2014
Congenital anterior urethrocutaneous fistula (CAUF) of the male urethra is a rare anomaly. CAUF can be defined as a urethral fistula in which the urethra and external urethral meatus are intact, typically with intact prepuce and no history of any penile ...
Hamdan H Alhazmi
doaj   +1 more source

Pilonidal fistulas mimicking fistulas-in-ano

Journal of British Surgery, 1982
Abstract Four pilonidal fistulas which were initially diagnosed as fistulas-in-ano are reported. Only one perianal pilonidal fistula and four perineal pilonidal sinuses have previously been reported. It is suggested that they are more common than the literature suggests and should be excluded when patients present with symptoms of ...
openaire   +2 more sources