Results 61 to 70 of about 2,066 (153)

Evidence Suggests Prophylactic Antibiotics May Be Unnecessary in Anorectal Surgery—A Systematic Review and Meta‐Analysis

World Journal of Surgery, Volume 50, Issue 3, Page 587-597, March 2026.
Current evidence does not support the routine use of prophylactic antibiotics in uncomplicated anorectal procedures. However, the certainty of evidence is limited by small sample sizes, methodological heterogeneity, and limited number of available studies. Large‐scale randomized trials are required to strengthen this evidence base.
James Jin, Velia Men, Maggie Wang, Andrew Hill   +3 more
wiley   +1 more source

Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Stem cells offer multifaceted therapeutic approaches for inflammatory diseases, each exhibiting distinct therapeutic properties. Hematopoietic stem cells, primarily through hematopoietic stem cell transplantation (HSCT), can effectively remodel the immune environment, showing particular promise in treating genetically linked cases.
Chen Wu, Zhi‐Ping Jin, Shu‐Qiang Weng, Ji‐Min Zhu, Ling Dong   +4 more
wiley   +1 more source

Influence of the cotton and silastic seton on the distance of the anal sphincter cables after fistulotomy in rats

Journal of Coloproctology, 2020
Rationale: Fistulotomy is a procedure widely used in the treatment of anal fistulas but is associated with varying degrees of fecal incontinence that could be minimized by previous use of sedentum, and the material used may influence the outcome ...
Ana Laura Sanches Lima, Beatriz Schorro Gianini, Bruna Miranda Santana, Carlos Henrique Marques dos Santos, Doroty Mesquita Dourado, Juliano Seger Falcão, Lucas Bannwart, Sara Jéssica Falcão Câmara   +7 more
doaj   +1 more source

Autologous skin graft intersphincteric implantation in anal fistula treatment (ASGIIFT) – A novel surgical technique in the treatment of complex transsphincteric anal fistulas

Colorectal Disease, Volume 28, Issue 2, February 2026.
Abstract Aim This study aimed to evaluate whether implantation of an autologous skin graft in the intersphincteric space, as part of the ASGIIFT procedure, improves the primary healing of complex transsphincteric cryptoglandular anal fistulas. Methods A prospective observational IDEAL stage 2a study was conducted at a tertiary referral centre for ...
Damir Karlović, Dorian Kršul, Dora Fučkar Čupić, Marko Zelić   +3 more
wiley   +1 more source

Comparative study on efficacy of fistulotomy and Ligation of intersphincteric fistula tract (LIFT) procedure in management of fistula-in-ano

, 2017
Background: Fistula-in-ano is one of the most common benign anal conditions in daily surgical practice. Present study aims at comparing the efficacy of open fistulotomy and ligation of intersphincteric fistula tract (LIFT) procedure based on its post ...
Balasubrahmanya K. S., Vinay G.
core   +1 more source

ERCP Performed Out‐of‐Working Hours Is Effective and Reliable for the Treatment of Acute Cholangitis

Gastroenterology Research and Practice, Volume 2026, Issue 1, 2026.
Background Acute cholangitis is a life‐threatening condition that requires prompt biliary drainage, typically achieved through endoscopic retrograde cholangiopancreatography (ERCP). However, data on outcomes of procedures performed outside of regular working hours remain limited. This study evaluates the safety and efficacy of out‐of‐working‐hours ERCP
Kerem Kenarlı, Bülent Ödemiş, Dilara Turan Gökçe, Orhan Coşkun, Volkan Gökbulut, Zeki Mesut Yalin Kılıç, Sreeja Dattachoudhury   +6 more
wiley   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists Are Associated With Improved Outcomes in Inflammatory Bowel Disease

GastroHep, Volume 2026, Issue 1, 2026.
Background The co‐existence of diabetes and obesity in patients with inflammatory bowel disease (IBD) increases morbidity and mortality associated with IBD, yet it remains unclear how medications used to treat these metabolic disorders affect IBD course.
Michael Saadeh, Apoorva Krishna Chandar, Revital Gorodeski Baskin, Jeffry Katz, Fabio Cominelli, Emad Mansoor, Miguel Regueiro, Vu Quang Nguyen, Than Than Aye   +8 more
wiley   +1 more source

Fistulotomy versus fistulectomy for simple fistula in ano: a retrospective cohort study [PDF]

, 2017
OBJECTIVE: To compare fistulotomy with fistulectomy for wound healing, duration of surgery, post-operative pain, incontinence and recurrence in patients with fistula in ano.
Ansari, Sumaiya, Haider, Batool A., Shaikh, F A, Murtaza, Ghulam, Chawla, Tabish, Shahzad, Noman   +5 more
core  

Prognostic Value of Serum Insulin‐Like Growth Factor‐1 in Patients With Anal Fistula Treated by Incision‐Thread‐Drawing Surgery

Annals of Gastroenterological Surgery, Volume 9, Issue 6, Page 1362-1368, November 2025.
IGF‐1 levels above 174.9 ng/mL were associated with better wound healing and lower postoperative inflammation. Higher IGF‐1 levels correlated with improved anal function at 7 and 14 days post‐surgery. ABSTRACT Background Anal fistula is a chronic condition characterized by an abnormal tract between the anal canal and perianal skin, often leading to ...
Zhijun Wu, Xuexue Yin, Jing Li
wiley   +1 more source

COMPARATIVE OUTCOMES AND PARAMETERS OF DRAINING SETON VERSUS FISTULOTOMY IN TREATING ANAL FISTULAS

Background:Anal fistula is a common anorectal condition associated with significant morbidity and recurrence. Draining seton placement and fistulotomy are widely used surgical treatment options, but their comparative outcomes remain a subject
Dr.Ritismita Mistry, Dr.Pankil Mota
core   +1 more source