Results 31 to 40 of about 10,624,441 (235)

Spatial Expression of Assembly Geometric Errors for Multi-axis Machine Tool Based on Kinematic Jacobian-Torsor Model

open access: yesChinese Journal of Mechanical Engineering, 2023
Assembly geometric error as a part of the machine tool system errors has a significant influence on the machining accuracy of the multi-axis machine tool.
Ang Tian   +4 more
doaj   +1 more source

Machine Tool Volumetric Error Features Extraction and Classification Using Principal Component Analysis and K-Means

open access: yesJournal of Manufacturing and Materials Processing, 2018
Volumetric errors (VE) are related to the machine tool accuracy state. Extracting features from the complex VE data provides with a means to characterize this data. VE feature classification can reveal the machine tool accuracy states.
Kanglin Xing   +2 more
doaj   +1 more source

Effect of the Stiffness of the Turntable Bearing Joint on the Dynamic Characteristics of the Five-Axis Machine Tool Rotary System

open access: yesMachines, 2023
The positioning accuracy and machining performance of the five-axis machine tool are significantly impacted by the dynamic characteristics of the rotary system of the two-axis rotary table machine. In this study, first, the stiffness of the joint bearing
Shi Wu   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Sidney Machine Tool Company photograph collage

open access: yes
A collage of photographs of men using equipment at the Sidney Machine Tool Company. Sidney Tool Company was founded in 1905 by Alfred C. Getz in Sidney, Ohio. Getz was also acting plant manager for Monarch Machine Tool, also in Sidney, during the same
Sidney Machine Tool Company
core   +4 more sources

Kinematic modeling of hybrid parallel serial five-axis machine tool [PDF]

open access: yesFME Transactions, 2013
Compared with serial structured machine tools and robots, parallel kinematic machine tools and robots have many advantages. Many different topologies of parallel mechanisms with 3-6 DOF have been used.
Milutinović Milan   +2 more
doaj  

Multi-axis synchronous interpolation feed rate adaptive planning with rotational tool center point function under comprehensive constraints

open access: yesAdvances in Mechanical Engineering, 2017
Real-time nonlinear error caused by rotation axis motion in five-axis interpolation can be compensated by rotational tool center point function.
Zhongquan Shi, Wenhua Ye, Ruijun Liang
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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