Results 81 to 90 of about 47,139 (341)

The application of ANFIS prediction models for thermal error compensation on CNC machine tools [PDF]

open access: yes, 2014
Thermal errors can have significant effects on CNC machine tool accuracy. The errors come from thermal deformations of the machine elements caused by heat sources within the machine structure or from ambient temperature change.
Abdulshahed   +35 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

An attempt to relate dynamic tracking error to occurring situation based on additional rectilinear motion for five-axis machine tools

open access: yesAdvances in Mechanical Engineering, 2020
During five-axis CNC machining, the dynamic tracking error of the five-axis machine tool caused by imperfect servo dynamic performance is the major factor affecting the accuracy during high-speed and high-precision manufacturing.
Qicheng Ding   +3 more
doaj   +1 more source

Development of Pitch Cycle-Based Iterative Learning Contour Control for Thread Milling Operations in CNC Machine Tools

open access: yesApplied Sciences, 2023
The helical contour motion accuracy of feed drive axes is important for thread milling operations in computer numerical control (CNC) machine tools. However, the motion dynamics and external disturbances significantly affect the contour motion results ...
Syh-Shiuh Yeh, Wei-Jia Jiang
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Study on a high thrust force bi-double-sided permanent magnet linear synchronous motor

open access: yesAdvances in Mechanical Engineering, 2016
A high thrust force bi-double-sided permanent magnet linear synchronous motor used in gantry-type five-axis machining center is designed and its performance was tested in this article.
Liang Tong, Muyi Lin
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Learning-Based Prediction of Pose-Dependent Dynamics

open access: yesJournal of Manufacturing and Materials Processing, 2020
The constantly increasing demand for both, higher production output and more complex product geometries, which can only be achieved using five-axis milling processes, requires elaborated analysis approaches to optimize the regarded process.
Felix Finkeldey   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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