Results 21 to 30 of about 6,104,615 (215)

Five-axis machining on CNC milling machines [PDF]

, 2017
В настоящее время, детали машин становятся все более сложными и точными. Это требует развития новых технологий механической обработки. В этих условиях многоосевая обработка на фрезерных станках с ЧПУ является одной из таких технологий.
Криворучко, Дмитрий Владимирович, Бондарь, Инна Владимировна, Dmitrij Krivoruchko, Inna Bondar   +3 more
core   +1 more source

Machining tests to identify kinematic errors on five-axis machine tools [PDF]

, 2010
The machining of a cone frustum as specified in National Aerospace Standard (NAS) 979 is widely accepted as a final performance test for five-axis machining centers.
Matsubara, Atsushi, Sawada, Masahiro, Matsushita, Tetsuya, Ibaraki, Soichi, Tetsuya Matsushita, Masahiro Sawada, Soichi Ibaraki, Atsushi Matsubara   +7 more
core   +1 more source

A design of five axis machining chuck

, 2021
This thesis deals with construction for five-axis machining. Objective was to design self-centering vise for five-axis milling. Thesis then includes overwiew of five-axis clamping and selection of manufacturers these clamping jigs.
Holec, Štěpán
core   +1 more source

A Multidimensional Performance Evaluation Method for Blade‑Specialized Five‑Axis Machining Centers

Nanjing Hangkong Hangtian Daxue Xuebao
Machining of aero‑engine blade‑type complex curved‑surface parts places stringent requirements for high accuracy， stability， and efficiency on five‑axis CNC machine tools. To assess the suitability of domestic five‑axis CNC equipment for this application，
LIN Zhiqiang, LU Chengbin, LI Jia, ZHANG Jiacheng, WU Qixun, ZHAO Guolong   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A Comparison Study on the Orientation Capability and Parasitic Motions of Two Novel Articulated Tool Heads with Parallel Kinematics

Advances in Mechanical Engineering, 2013
This paper proposes two novel articulated tool heads based on three degree-of-freedom (DoF) parallel kinematic mechanisms (PKMs). They can realize one translation and the A/B-axis (rotations about the x - and y -axes) linkage movements.
Fugui Xie, Xin-Jun Liu, Tiemin Li
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Research on Continuous Machining Strategy for Five-Axis Machine Tool: Five-Axis Linkage to Four-Axis Linkage

, 2023
The article presents a novel strategy for enhancing the efficiency of machines that are used for complex structure machining. It proposes a low-cost five-axis four-linkage milling system as an alternative to the more expensive five-axis five-linkage ...
Jiang Liu, Jiashang Dong, Manxian Liu, Liang Ji, Yesong Wang   +4 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Automatic planning for machine tool calibration: A case study [PDF]

, 2012
Machine tool owners require knowledge of their machine’s capabilities, and the emphasis increases with areas of high accuracy manufacturing. An aspect of a machine’s capability is its geometric accuracy. International Standards and best-practice guides
P. Gregory, Parkinson, Simon, Fletcher, Simon, S. Fletcher, Crampton, Andrew, Fletcher, S., A. Crampton, Longstaff, Andrew P., S. Parkinson, Gregory, Peter, A.P. Longstaff, Crampton, A.; id_orcid, Longstaff, A. P.; id_orcid, Parkinson, S.   +13 more
core   +1 more source