Results 101 to 110 of about 5,309,315 (254)
Spatial patterns in thunderstorm rainfall events and their coupling with watershed hydrological response [PDF]
, 2006 Weather radar systems provide detailed information on spatial rainfall patterns known to play a significant role in runoff generation processes. In the current study, we present an innovative approach to exploit spatial rainfall information of air mass ...
Gao, X +5 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Cross-cultural personality differences between East Asia and Northern Europe in IPIP-NEO
International Journal of Personality Psychology, 2017 Psychological differences between nations are part of the challenges of globalization. The present study provides benchmarks of personality traits across 12 nations in East Asia and Northern Europe (N = 23,268). Personality was measured with the IPIP-NEO-
Petri J. Kajonius
doaj
Substitution in Markusen's classic trade and factor movement complementarity models [PDF]
Mundell and Markusen each wrote classic papers on the relationship between trade and factor movement. Mundell showed that substitution holds in the Heckscher-Ohlin model.
Schiff, Maurice
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Frontiers in PsychologyThis article aims to thoroughly understand the concept of emotional self-regulation (ESR) and its relationship with personality. Through an interdisciplinary dialogue between psychology and philosophy—specifically, the anthropology of Thomas Aquinas ...
Juan Pablo Rojas-Saffie +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Five-factor model personality traits and cognitive function in five domains in older adulthood
BMC Geriatrics, 2019 Background Five-factor model (FFM) personality traits have been associated consistently with risk of Alzheimer’s disease and related dementias (ADRD). Less is known about how these traits are associated with functioning in specific domains of cognitive ...
Angelina R. Sutin +3 more
doaj +1 more source