Results 51 to 60 of about 41,010 (298)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Comparison between flying capacitor and modular multilevel inverter [PDF]

open access: yes, 2009
The paper describes the operational principle of flying capacitor and modular multilevel inverters. The detailed discussions of dc link capacitors voltage balancing methods for both inverters are given in order to enable fair comparison. The causes of dc
Adam, G.P.   +5 more
core  

Solar Photovoltaic and Thermal Energy Systems: Current Technology and Future Trends [PDF]

open access: yes, 2017
Solar systems have become very competitive solutions for residential, commercial, and industrial applications for both standalone and grid connected operations. This paper presents an overview of the current status and future perspectives of solar energy
Abu.Rub, Aitham   +2 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Overview of three-phase inverter topologies for distributed generation purposes [PDF]

open access: yes, 2010
The increasing presence of single-phase distributed generators and unbalanced loads in the electric power system may lead to unbalance of the three phase voltages, resulting in increased losses and heating.
De Kooning, Jeroen   +5 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A five‐level nested neutral point‐clamped inverter topology

open access: yesIET Power Electronics
Classical five‐level nested neutral point‐clamped (5L NNPC) inverter‐leg is a hybrid of the flying‐capacitor and diode‐clamped 5‐L inverter‐leg configurations.
Desmond O. Obe   +3 more
doaj   +1 more source

Investigation of Highly Efficient Five Level Asymmetrical Inverter Family With Embedded Buck-Boost Converter

open access: yesIEEE Access, 2022
In recent years, focus is given to the increment of the power conversion efficiency of multilevel inverters with integrated voltage boosting characteristics.
Theodoros P. Mouselinos   +1 more
doaj   +1 more source

Design and Development of a Class EF2 Inverter and Rectifier for Multi-megahertz Wireless Power Transfer Systems [PDF]

open access: yes, 2016
This paper presents the design and implementation of a Class EF2 inverter and Class EF2 rectifier for two -W wireless power transfer (WPT) systems, one operating at 6.78 MHz and the other at 27.12 MHz.
Aldhaher, S, Mitcheson, PD, Yates, DC
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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