Results 91 to 100 of about 5,309,315 (254)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Big Five Personality Traits, Personal Projects, and Compulsive Buying: A Causal Approach

open access: yesEuropean Journal of Investigation in Health, Psychology and Education
The purpose of this paper is to predict compulsive buying based on the integration of explanatory units located at different levels of personality analysis (dispositional vs. motivational variables).
José Manuel Otero-López   +2 more
doaj   +1 more source

Relações hierárquicas entre os traços amplos do Big Five Hierarchical relationship between the broad traits of the Big Five

open access: yesPsicologia: Reflexão e Crítica, 2012
O modelo Big Five sustenta que a personalidade humana é composta por dezenas de fatores específicos. Apesar dessa diversidade, esses fatores confluem para cinco traços amplos que estão em um mesmo nível de hierarquia.
Cristiano Mauro Assis Gomes   +1 more
doaj   +1 more source

Development and validation of the social emotional competence questionnaire (SECQ) [PDF]

open access: yes, 2012
Reliable and valid measures of children’s and adolescents’ social emotional competence (SEC) are necessary to develop in order to assess their social emotional development and provide appropriate intervention in child and adolescent development.
Ee, Jessie, Zhou, Mingming
core  

Normal State Spin Dynamics of Five-band Model for Iron-pnictides

open access: yes, 2008
Normal state spin dynamics of the recently discovered iron-pnictide superconductors is discussed by calculating spin structure factor S(q, omega) in an itinerant five-band model within RPA approximation.
Ding H.   +26 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Functional Connectome of the Five-Factor Model of Personality

open access: yesPersonality Neuroscience, 2018
A key objective of the emerging field of personality neuroscience is to link the great variety of the enduring dispositions of human behaviour with reliable markers of brain function.
Nicola Toschi   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Trichotillomania and personality traits from the five-factor model

open access: yesBrazilian Journal of Psychiatry, 2015
Objective:To examine whether personality traits have predictive validity for trichotillomania (TTM) diagnosis, pulling severity and control, and hair pulling style.Methods:In study 1, logistic regression was used with TTM cases (n=54) and controls (n=25)
Nancy J. Keuthen   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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