Results 61 to 70 of about 5,888,630 (298)

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Testing asset pricing models on the Pakistan Stock Exchange

open access: yesBusiness Review, 2018
This study investigates the performance of CAPM, three-factor and five-factor asset pricing models on the Pakistan Stock Exchange using monthly data of 896 companies from November 2000 to December 2016.
Kiran Lohano , Muhammad Kashif
doaj   +1 more source

Smoking and the Five‐Factor Model of personality [PDF]

open access: yesAddiction, 2004
ABSTRACTAims  Investigating the association between personality traits and smoking status using a comprehensive model of personality, the Five‐Factor Model (FFM).Design  Cross‐sectional survey.Setting  Baltimore, MD, USA.Participants  Adult elderly Americans (n = 1638).Measurements  A self‐administered survey on cigarette smoking and the Revised NEO ...
Antonio, Terracciano, Paul T, Costa
openaire   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Incremental validity of positive orientation: predictive efficiency beyond the five-factor model

open access: yesHealth Psychology Report, 2016
Background The relation of positive orientation (a basic predisposition to think positively of oneself, one’s life and one’s future) and personality traits is still disputable.
Łukasz Roland Miciuk   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The General Factor of Personality: Ten Years After

open access: yesPsychological Topics, 2017
According to the empirical and theoretical research in past ten years, the General Factor of Personality (GFP) was interpreted as the highest-order (most general) personality dimension, which occupies the apex of the structural hierarchy of personality ...
Janek Musek
doaj   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

An investigation of five types of personality trait continuity: A two-wave longitudinal study of Spanish adolescents from age 12 to age 15

open access: yesFrontiers in Psychology, 2016
The present study investigated five types of personality trait continuity using two measurement waves of Spanish adolescents (N = 234). Personality traits were measured with the short form of the Junior Spanish NEO-PI-R (JS NEO-S) at ages 12 and 15.
Manuel Ignacio Ibáñez   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy