Results 51 to 60 of about 868,399 (310)

Personality differentiation by cognitive ability:An application of the moderated factor model [PDF]

, 2016
The personality differentiation hypothesis holds that at higher levels of intellectual ability, personality structure is more differentiated. We tested differentiation at the primary and global factor levels in the US standardisation sample of the 16PF5 (
Booth, Thomas, Molenaar, Dylan, Murray, Aja Louise   +2 more
core   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Unusual configurations of personality traits Indicate multiple patterns of their coalescence [PDF]

, 2018
It is widely accepted that the Five Factor Model (FFM) is a satisfactory description of the pattern of covariations among personality traits, which supposedly fits, more or less adequately, every individual.
Allik, Jüri, Hřebíčková, Martina, Realo, Anu   +2 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Ethics-Relevant Values as Antecedents of Personality Change: Longitudinal Findings from the Life and Time Study

Collabra: Psychology, 2019
What leads personality to develop in adulthood? Values, guiding principles that apply across contexts, may capture motivation for growth and change. An essentialist trait perspective posits that personality changes only as a result of organic factors ...
Amber Gayle Thalmayer, Gerard Saucier, John C. Flournoy, Sanjay Srivastava   +3 more
doaj   +1 more source

Five-Factor Model of Personality and Sexual Aggression

International Journal of Offender Therapy and Comparative Criminology, 2013
Despite several studies have used the five-factor model (FFM) of personality as theoretical background, few studies have been conducted on the topic of the FFM and sexual aggression. This study explored how the big five dimensions and features of emotional adjustment characterize different forms of sexual violence.
Joana Carvalho, Pedro Nobre
openaire   +3 more sources

Hierarchical structure of maladaptive personality traits in older adults: joint factor analysis of the PID-5 and the DAPP-BQ [PDF]

, 2014
In DSM-5, the categorical model and criteria for the 10 personality disorders included in DSM-IV will be reprinted in Section II. Moreover, an alternative dimensional classification model will appear in Section III.
Bastiaansen, Leen, De Clercq, Barbara, Dierckx, Eva, Hofmans, Joeri, Rossi, Gina, Van den Broeck, Joke   +5 more
core   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Analysis of the Relationship between Higher-Order Factor Structure of Personality Disorders and the Five-Factor Model of Personality

Brain Sciences, 2023
The growing body of evidence on the dimensional classification of personality disorders (PD) has resulted in its acceptance in the ICD-11 classification, which abolished categories and retains only a general description of PD.
Danilo Pešić, Dušica Lečić-Toševski, Marko Kalanj, Ivan Ristić, Olivera Vuković, Bojana Pejušković   +5 more
doaj   +1 more source

Association between the five factor personality dimensions and psychopathology symptoms [PDF]

, 2019
Treball Final de Grau en Psicologia. Codi: PS1048. Curs: 2018/2019.The 53-item Brief Symptom Inventory (BSI-53), a shorter version of the revised version of the Symptom Checklist-90 (SCL-90-R), is a widely used questionnaire that measures the ...
Canós Badenes, Ana
core