Results 51 to 60 of about 873,049 (261)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Personality in Soccer: Investigation of the Five-Factor Model of Personality in High-Level Athletes

Frontiers in Sports and Active Living, 2022
BackgroundIn high-level sports, rapid screening and diagnostic instruments are necessary considering limited access that researchers have to these athletes.
Jan Spielmann, Jan Spielmann, Adam Beavan, Jan Mayer, Jan Mayer   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The Relationship Between Adolescent’ Five Personality Traits With Social Self-Efficacy, Cognitive Errors and Five Personality Traits of Parents

Gaziantep Üniversitesi Sosyal Bilimler Dergisi, 2017
The purpose of this study, to investigate the relationship between adolescent five personality traits with social self-efficacy, cognitive errors, cognitive flexibility and five personality of parents.
Mehmet Bilgin
doaj   +1 more source

Does the Leader Make a Difference? Relationship Between Executive Leader Personality and Entrepreneurial Firm Performance [PDF]

, 1998
The purpose of this study was to expand research on personality and leadership by investigating the relationship between executive leader personality and firm performance.
Cavanaugh , Marcie A., Judge, Timothy A., Welbourne, Theresa M.   +2 more
core   +2 more sources

History of the Diagnosis of a Sexually Transmitted Disease is Linked to Normal Variation in Personality Traits [PDF]

, 2012
Introduction. Stable individual differences in personality traits have well-documented associations with various aspects of health. One of the health outcomes that directly depends on people's behavioral choices, and may therefore be linked to ...
Allik, Andres Metspalu, Anu Realo, Bjekic, Bogg, Connolly, Conrod, Costa, De Fruyt, De Genna, Deary, Distel, Ericksen, Fenton, Fenton, Goodwin, Hagger‐Johnson, Hagger‐Johnson, Harned, Hill, Hoyle, Jüri Allik, Kallasmaa, Kendler, Laisaar, Lykken, Malouff, Marrazzo, McCrae, McCrae, Mõttus, O'Connor, O'Connor, René Mõttus, Riemann, Roberts, Schmitt, Schmitt, Sherman, Sutin, Terracciano, Trobst, Tõnu Esko   +42 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Personality traits of patients with myocardial infarctio A case-control study

مجله دانشگاه علوم پزشکی بیرجند, 2013
Background and Aim: In addition to some physiological factors such as hypertension, obesity, hyperlipdemia, and smoking. Psychological factors, especially personality traits of individuals, also accelerate and intensify cardiovascular diseases.
Sedigheh Eshraghi, Ahmad Khamosan, Reza Dastjerdy, Morteza Vejdan, Toba Kazemi   +4 more
doaj  

An investigation of five types of personality trait continuity: A two-wave longitudinal study of Spanish adolescents from age 12 to age 15

Frontiers in Psychology, 2016
The present study investigated five types of personality trait continuity using two measurement waves of Spanish adolescents (N = 234). Personality traits were measured with the short form of the Junior Spanish NEO-PI-R (JS NEO-S) at ages 12 and 15.
Manuel Ignacio Ibáñez, Ana María Viruela, Laura eMezquita, Jorge eMoya, Helena eVilla, Laura eCamacho, Generós eOrtet   +6 more
doaj   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source