Results 101 to 110 of about 472,647 (332)

Word sense disambiguation and information retrieval [PDF]

open access: yes, 1914
It has often been thought that word sense ambiguity is a cause of poor performance in Information Retrieval (IR) systems. The belief is that if ambiguous words can be correctly disambiguated, IR performance will increase.
Sanderson, M.
core   +1 more source

Endoscopic trans‐canal facial nerve decompression in Melkersson–Rosenthal syndrome: A novel approach

open access: yesClinical Case Reports
Key Clinical Message Melkersson–Rosenthal syndrome can cause recurring bilateral facial paralysis. When steroids fail, surgical decompression of facial nerve is recommended, with endoscopic trans‐canal decompression as a safe, minimally invasive, and ...
Alimohamad Asghari   +4 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Waitara : a sense of place in 1998 : a thesis presented in partial fulfilment of the requirements for the degree of Master of Resource and Environmental Planning at Massey University [PDF]

open access: yes, 1999
This study investigates and describes "senses of place" as experienced by 13 long- term Pakeha residents of Waitara in 1998. The town of Waitara is located on the West Coast of the North Island in New Zealand, and at the 1996 census had a population of 6,
Young, Denise Catherine
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Assessing the impact of the five senses on quality of life in mucopolysaccharidoses. [PDF]

open access: yesOrphanet J Rare Dis, 2020
Giugliani R   +3 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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