Results 51 to 60 of about 48,579 (308)
Türk Oftalmoloji Dergisi, 2022 This case report aims to describe a modified continuous suturing technique for firm fixation of a human amniotic membrane graft in a patient with persistent epithelial defect (PED) after a chemical eye injury.
Mehmet Baykara +3 more
doaj +1 more source
Average magnitude of fixation errors induced by different types of ocular events.
, 2014 Fixation errors associated with blinks tended to be larger than those associated with (all) microsaccades or drifts, but not significantly so.Average magnitude of fixation errors induced by different types of ocular events.
Sharon M. Crook (647623) +7 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Development of a limbal fixation mechanism for a minimally invasive implantable glaucoma microstent
Current Directions in Biomedical Engineering, 2020 Glaucoma represents a chronic eye disease that becomes increasingly prevalent worldwide. Therapies are commonly based on the reduction of intraocular pressure (IOP). Implant devices for micro-invasive glaucoma surgery (MIGS) represent a promising therapy
Siewert Stefan +11 more
doaj +1 more source
Vision Research, 2006 Eye movements during fixation were recorded in 55 normal subjects with ages ranging from 21 to 81 years. We analysed ocular fixation recordings using measurements of saccadic intrusion amplitudes and frequencies along with fixation periods and mean fixation displacement.
Canice McGivern, R., Mark Gibson, J.
openaire +2 more sources
Formalin Fixation and Cryosectioning Cause Only Minimal Changes in Shape or Size of Ocular Tissues
, 2017 Advances in imaging have made it increasingly common to study soft tissues without first embedding them in plastic or paraffin and without using labels or stains.
Danielle Hu +7 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Theoretical Issues and Methodological Implications in Researching Visual Search Behaviours: A Preliminary Study Comparing the Cognitive and Ecologic Paradigms [PDF]
Montenegrin Journal of Sports Science and Medicine, 2013 A number of research papers have been devoted to understanding the mechanisms underpinning successful decision-making in sports, and analysis of eye movements has deserved special attention in this concern.
José Afonso
doaj