Results 51 to 60 of about 447,001 (304)

Fixational eye movements and binocular vision

Frontiers in Integrative Neuroscience, 2014
During attempted visual fixation, small involuntary eye movements –called fixational eye movements--continuously change of our gaze’s position. Disagreement between the left and right eye positions during such motions can produce diplopia (double vision).
Jorge eOtero-Millan, Jorge eOtero-Millan, Stephen eMacknik, Susana eMartinez-Conde   +3 more
doaj   +1 more source

A simple saccadic reading test to assess ocular motor function in cerebellar ataxia. [PDF]

PLoS ONE, 2018
Cerebellar ataxia is a neurological disorder due to dysfunction of the cerebellum that affects coordination of fine movement, gait, and balance. Although ataxic patients commonly exhibit abnormal eye movement and have difficulties with saccadic reading ...
Angela Jinsook Oh, Tiffany Chen, Mohammad Ali Shariati, Naz Jehangir, Thomas N Hwang, Yaping Joyce Liao   +5 more
doaj   +1 more source

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells [PDF]

, 2008
The protein product of the ocular albinism type 1 gene, named OA1, is a pigment cell-specific G protein-coupled receptor exclusively localized to intracellular organelles, namely lysosomes and melanosomes.
Bennett, DC, Venturi C, Palmigiano, A, Schiaffino, MV, Piccirillo, R, Altimare D., Rotondo G., Tacchetti, C, Marigo, V, Bagnato P., Coppola M., Rotondo, G, Venturi, C, Sviderskaya, EV, Palmisano I., Palmigiano A., Altimare D, Bagnato, P, Marigo V., Surace, EM, Altimare, D, Tacchetti C, Innamorati G., Venturi C., Surace E. M., Palmisano I, Rotondo G, INNAMORATI, Giulio, BALLABIO, ANDREA, Schiaffino M. V., Sviderskaya E. V., Palmigiano A, Innamorati G, SURACE, Enrico Maria, Sviderskaya EV, Piccirillo R, Bagnato P, Ballabio A., Incerti B, Piccirillo R., Tacchetti C., Schiaffino MV, Coppola, M, Incerti, B, Bennett DC, Incerti B., Palmisano, I, Coppola M, Bennett D. C., Innamorati, G, Ballabio, A, Marigo V   +51 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Oculomotor responses and 3D displays [PDF]

, 1998
This thesis investigated some of the eye movement factors related to the development and use of eye pointing devices with three dimensional displays (stereoscopic and linear perspective).
Fulford, Katy A.
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Effect of Small Angle Misalignments on Ocular Wavefront Zernike Coefficients

Photonics
Purpose: To assess the possible impact of minor changes in fixation on wavefront measurements as a potential constraint in detecting subtle temporal variations in ocular wavefront error.
Ebrahim Safarian Baloujeh, Francisco J. Ávila, José M. González-Méijome   +2 more
doaj   +1 more source

Sticking with autologous serum versus stitching with non-absorbable suture conjunctival limbal autograft in primary pterygium surgery

GAIMS Journal of Medical Sciences, 2022
Background: Pterygium is a degenerative ocular surface disorder with wing shaped fibrovascular growth of the subconjunctival tissue onto the cornea. Objectives: The purpose of this study was to compare the surgical outcome of suture less technique ...
Bansari Sorathiya, Kavita Shah, Naurin Memon, Meet Parikh   +3 more
doaj   +1 more source

Markov Models for Ocular Fixation Locations in the Presence and Absence of Colour [PDF]

Journal of the Royal Statistical Society Series C: Applied Statistics, 2017
SummaryIn response to the 2015 Royal Statistical Society's statistical analytics challenge, we propose to model the fixation locations of the human eye when observing a still image by a Markov point process in R2. Our approach is data driven using k-means clustering of the fixation locations to identify distinct salient regions of the image, which in ...
Kashlak, Adam B., Devane, Eoin, Dietert, Helge, Jackson, Henry   +3 more
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source