Results 51 to 60 of about 2,698,073 (240)

Biomechanical investigation of dynamic hip screw and wire fixation on an unstable intertrochanteric fracture

BioMedical Engineering OnLine, 2019
Background Although use of a dynamic hip screw (DHS) for stable intertrochanteric hip fracture fixation has been successfully applied in fracture healing for more than 20 years, DHS fixation on unstable intertrochanteric fractures still has a high ...
Hsu-Fu Wu, Chih-Han Chang, Gwo-Jaw Wang, Kuo-An Lai, Chung-Hwan Chen   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Evaluation of the macular sensitivity and retinal ganglion cell layer in unilateral amblyopia

Indian Journal of Ophthalmology
Purpose: To assess macular sensitivity and fixation pattern obtained by microperimetry and ganglion cell complex (GCC) obtained by optical coherence tomography (OCT) in cases with unilateral amblyopia and to compare with control.
Nilay Çiçek, Bengi Demirayak, Fadime U Yigit   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Reading Assessment and Eye Movement Analysis in Bilateral Central Scotoma Due to Age-Related Macular Degeneration

Journal of Eye Movement Research
This study investigates reading performances and eye movements in individuals with eccentric fixation due to age-related macular degeneration (AMD). Overall, 17 individuals with bilateral AMD (7 males; mean age 77.47 ± 5.96 years) and 17 controls (10 ...
Polona Zaletel Benda, Grega Jakus, Jaka Sodnik, Nadica Miljković, Ilija Tanasković, Smilja Stokanović, Andrej Meglič, Nataša Vidovič Valentinčič, Polona Jaki Mekjavić   +8 more
doaj   +1 more source

Effect of Plate and Screw Fixation on Stability of Weber B/Supination-External Rotation Fractures with Partial Deltoid Ligament Injury (SER4a): Robotic-Based Joint Testing

Foot & Ankle Orthopaedics, 2023
Category: Trauma; Ankle Introduction/Purpose: Fibular fractures with signs of concomitant deltoid ligament injury have been operated on with plate and screw fixation of the fibula for decades.
Martin Greger Gregersen PT, MSc, Andreas Fagerhaug Dalen MD, Fredrik Nilsen MD, PhD, Marius Molund MD, PhD   +3 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Nitrogen fixation and nitrogenase activity of Azotobacter chroococcum [PDF]

, 1974
The purpose of the present investigation was to study the effect of some chemical, physical and biological factors on growth, efficiency of nitrogen fixation and nitrogenase activity of Azotobacter chroococcum.From biochemical studies with cell-free ...
Brotonegoro, S.
core  

Enhancing the Ilizarov Apparatus: Mechanical Stiffness

مجلة النهرين للعلوم الهندسية
The Ilizarov system is a form of external fixation device utilized by medical professionals to aid patients who have sustained injuries from accidents, bone shortening, or nonunion of the bone.
Alaa A. Najim, Sadiq J. Hamandi, Ahmed Alzubaidi   +2 more
doaj   +1 more source