Results 41 to 50 of about 4,911,014 (257)

Dyskalemia Prior to and After Initiation of a Fixed Dose Combination of Telmisartan and Amlodipine in Adults with Hypertension in Bangladesh

Global Heart
Background: The World Health Organization recommends fixed-dose combination (FDC) pills for treating hypertension. Antihypertensive FDC pills often contain a renin-angiotensin inhibitor (RASI) or diuretic.
Junichi Ishigami, Md. Mahmudul Hasan, Aruna Sarker, Sharmin Nahar, Sibly Sadik Shuvo, Mir Ishraquzzaman, Mohammad Abdullah Al Mamun, Md. Kalimuddin, Sheikh Mohammad Mahbubus Sobhan, Di Zhao, Kunihiro Matsushita, Lawrence J. Appel, Sohel Reza Choudhury, Edgar R. Miller III, Fazila-Tun-Nesa Malik   +14 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Comparative study of the efficacy of olmesartan/amlodipine vs. perindopril/amlodipine in peripheral blood pressure after missed dose in type 2 diabetes [PDF]

, 2016
INTRODUCTION: Combination therapy is needed to control blood pressure (BP) in a large number of hypertensive patients with diabetes mellitus. Adherence to treatment is a major clinical problem; therefore, the time duration of the antihypertensive action ...
Pichler G, Redon J, Missed Dose Study Group, Sarzani Riccardo   +3 more
core   +2 more sources

Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Improves Exacerbation Outcomes in Patients with COPD without a Recent Exacerbation History: A Subgroup Analysis of KRONOS

International Journal of COPD, 2021
Fernando J Martinez,1 Gary T Ferguson,2 Eric Bourne,3 Shaila Ballal,4 Patrick Darken,5 Magnus Aurivillius,6 Paul Dorinsky,3 Colin Reisner4 1Joan and Sanford I.
Martinez FJ, Ferguson GT, Bourne E, Ballal S, Darken P, Aurivillius M, Dorinsky P, Reisner C   +7 more
doaj  

Chlorproguanil−Dapsone−Artesunate versus Artemether−Lumefantrine : a randomized, double-blind phase III trial in African children and adolescents with uncomplicated plasmodium falciparum malaria [PDF]

, 2009
Chlorproguanil−dapsone−artesunate (CDA) was developed as an affordable, simple, fixed-dose artemisinin-based combination therapy for use in Africa. This trial was a randomized parallel-group, double-blind, double-dummy study to compare CDA and artemether−
Peter A Winstanley, Pamba Allan, Guiguemdé, Robert, Stephan Duparc, Paula L Kirby, Esamai, Fabian, Ezedinachi, Emmanuel U, Ward, S.A., Umeh, Rich E., Borrmann Steffen, Winstanley Peter A., Kirby, Paula L., Kellam, Lynda, Premji, Z., Greenwood, Brian, Ward, Stephen A, Premji, Zul, Lynda Kellam, Ezedinachi Emmanuel U., Oguche, Stephen, Owusu-Agyei, S., Stephen Oguche, Greenwood Brian, Oguche Stephen, Owusu-Agyei Seth, Winstanley, Peter A, Oguche, S, Emmanuel U Ezedinachi, Pamba, Allan, Rich E Umeh, Greenwood, B., Umeh Rich E., Zul Premji, Kellam, L., Winstanley, P.A., Duparc, Stephan, Owusu-Agyei, Seth, Duparc Stephan, Guiguemdé Robert, Guiguemde, R., Ward, S. A., Umeh, Rich Enujioke, Allan Pamba, Ward, Steve, Fabian Esamai, Ezedinachi, Emmanuel U., Umeh, R.E., Stephen A Ward, Kellam Lynda, Premji Zul, Esamai Fabian, Duparc, S., Kirby Paula L., Sowunmi Akintunde, Kirby, Paula L, Brian Greenwood, Pamba, A., Kirby, P.L., Rénia, Laurent, Ward Stephen A., Borrmann, S., Seth Owusu-Agyei, Robert Guiguemdé, Akintunde Sowunmi, Sowunmi, Akintunde, Ezedinachi, E.U., Umeh, Rich E, Sowunmi, A., Oguche, S., Borrmann, Steffen, Esamai, F., Steffen Borrmann, Winstanley, Peter, Winstanley, Peter A.   +73 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The Role of Dexketoprofen/Tramadol in Multimodal Therapy to Prevent Acute Postsurgical and Acute Low Back Pain from Developing into Chronic Pain: A Delphi Consensus Study

Pain and Therapy
Introduction Dexketoprofen/tramadol is a fixed-dose multimodal combination analgesic that significantly controls multiple acute pain states, and may have an important clinical application in providing pain control adequate to prevent the transition from ...
Giustino Varrassi, Maria Dolma Gudez-Santos, Magdi Hanna, Magdalena Kocot-Kępska, Antonio Montero Matamala, Marco Antonio Narvaez Tamayo, Serge Perrot, the Delphi Study Group   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source