Results 41 to 50 of about 4,614 (253)

Bounded fixed-parameter tractability and reducibility

open access: yesAnnals of Pure and Applied Logic, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Rod Downey   +3 more
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Structural Parameterizations of the Biclique-Free Vertex Deletion Problem [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science
In this work, we study the Biclique-Free Vertex Deletion problem: Given a graph $G$ and integers $k$ and $i \le j$, find a set of at most $k$ vertices that intersects every (not necessarily induced) biclique $K_{i, j}$ in $G$.
Lito Goldmann   +2 more
doaj   +1 more source

Energy-efficient offloading and resource allocation for mobile edge computing enabled mission-critical internet-of-things systems

open access: yesEURASIP Journal on Wireless Communications and Networking, 2021
The energy cost minimization for mission-critical internet-of-things (IoT) in mobile edge computing (MEC) system is investigated in this work. Therein, short data packets are transmitted between the IoT devices and the access points (APs) to reduce ...
Yaru Fu   +6 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

The Parameterized Complexity of the Rainbow Subgraph Problem

open access: yesAlgorithms, 2015
The NP-hard RAINBOW SUBGRAPH problem, motivated from bioinformatics, is to find in an edge-colored graph a subgraph that contains each edge color exactly once and has at most \(k\) vertices.
Falk Hüffner   +3 more
doaj   +1 more source

On the Fixed-Parameter Tractability of Capacitated Clustering

open access: yesCoRR, 2019
We study the complexity of the classic capacitated k-median and k-means problems parameterized by the number of centers, k. These problems are notoriously difficult since the best known approximation bound for high dimensional Euclidean space and general metric space is $Θ(\log k)$ and it remains a major open problem whether a constant factor exists ...
Cohen-Addad, Vincent, Li, Jason
openaire   +5 more sources

Fixed-Parameter Tractability of Multicut in Directed Acyclic Graphs [PDF]

open access: yesSIAM Journal on Discrete Mathematics, 2012
The MULTICUT problem, given a graph G, a set of terminal pairs T={(s_i,t_i) | 1 <= i <= r} and an integer p, asks whether one can find a cutset consisting of at most p non-terminal vertices that separates all the terminal pairs, i.e., after removing the cutset, t_i is not reachable from s_i for each 1 <= i <= r.
Stefan Kratsch   +3 more
openaire   +7 more sources

Ontology‐Aligned Structuring and Reuse of Multimodal Materials Data and Workflows Toward Automatic Reproduction

open access: yesAdvanced Engineering Materials, EarlyView.
Reproduction of stacking fault energy calculations from literature with a semi‐automated large language model‐assisted extraction procedure: extraction of simulation protocol, atomistic structures, computational parameters, and reported results, ontology alignment, knowledge graph construction and, finally, recomputation forvalidation.
Sepideh Baghaee Ravari   +5 more
wiley   +1 more source

Rooted Cycle Bases

open access: yesJournal of Graph Algorithms and Applications, 2017
A cycle basis in an undirected graph is a minimal set of simple cycles whose symmetric differences include all Eulerian subgraphs of the given graph. We define a rooted cycle basis to be a cycle basis in which all cycles contain a specified root edge ...
David Eppstein   +2 more
doaj   +1 more source

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