MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
A configurable streaming spiking neural network accelerator with decoupled pixel-level and output-channel parallelism for automatic modulation classification. [PDF]
Yang K, Eltawil AM, Salama KN.
europepmc +1 more source
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
A two-step iterative framework for signal and image deblurring using G-I-Nonexpansive Mappings. [PDF]
Yolacan E.
europepmc +1 more source
Composition analysis of large samples with PGNAA using a fixed point iteration.
The composition problem in large sample prompt gamma neutron activation analysis (PGNAA) is a nonlinear inverse problem. The basic form of the nonlinear inverse composition problem is presented.
Akkurt, Hatice
core
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Fixed point approximation for generalized μ-Reich-Suzuki nonexpansive mappings with application. [PDF]
Ishtiaq T +3 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Adaptive Step-Size Tuning Combined with Ternary Search Optimization for FCS-MPC Sensorless Speed Estimation of PMSMs. [PDF]
Dang Z, Yang F, Ruan J, Tian M, Liu D.
europepmc +1 more source
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source

