Results 91 to 100 of about 2,017,440 (319)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
New Results and Generalizations for Approximate Fixed Point Property and Their Applications
Abstract and Applied Analysis, 2014 We first introduce the concept of manageable functions and then prove some new existence theorems related to approximate fixed point property for manageable functions and α-admissible multivalued maps. As applications of our results, some new fixed point
Wei-Shih Du, Farshid Khojasteh
doaj +1 more source
Some geometric properties concérning fixed point theory
Revista Matemática Complutense, 1996 The Fixed Point Theory for nonexpansive mappings is strongly based upon the geometry of the ambient Banach space. In section 1 we state the role which is played by the multidimensional convexity and smoothness in this theory. In section 2 we study the computation of the normal structure coefficient in finite dimensional lp-spaces and its connection ...
openaire +5 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
On Best Proximity Points under the -Property on Partially Ordered Metric Spaces
Abstract and Applied Analysis, 2013 Very recently, Abkar and Gabeleh (2013) observed that some best proximity point results under the -property can be obtained from the same results in fixed-point theory. In this paper, motivated by this mentioned work, we show that the most best proximity
Mohamed Jleli +2 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
The Fixed Point Property in Modal Logic
Notre Dame Journal of Formal Logic, 2001 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Quadruple fixed point theorems for nonlinear contractions on partial metric spaces
Applied General Topology, 2014 The notion of coupled fixed point was introduced by Guo and Laksmikantham [12]. Later Gnana Bhaskar and Lakshmikantham in [11] investigated the coupled fixed points in the setting of partially ordered set by defining the notion of mixed monotone property.
Erdal Karapinar, Kenan Tas
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Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source