Predicting cervical cancer DNA methylation from genetic data using multivariate CMMP
Abstract Epigenetic modifications link the environment to gene expression and play a crucial role in tumour development. DNA methylation, in particular, is gaining attention in cancer research, including cervical cancer, the focus of this study.
Hang Zhang +5 more
wiley +1 more source
A qualitative study on the stability and existence of solutions in a fractional-order water pollution model via the predictor-corrector approach. [PDF]
Iqbal N +3 more
europepmc +1 more source
An observation‐driven state‐space model for claims size modelling
Abstract State‐space models are popular in econometrics. Recently, these models have gained some popularity in the actuarial literature. The best known state‐space models are of the Kalman‐filter type. These are called parameter‐driven because the observations do not impact the state‐space dynamics.
Jae Youn Ahn +2 more
wiley +1 more source
Ricci curvature bounds and rigidity for non-smooth Riemannian and semi-Riemannian metrics. [PDF]
Kunzinger M, Ohanyan A, Vardabasso A.
europepmc +1 more source
Abstract We establish the consistency and the asymptotic distribution of the least squares estimators of the coefficients of a subset vector autoregressive process with exogenous variables (VARX). Using a martingale central limit theorem, we derive the asymptotic normal distribution of the estimators. Diagnostic checking is discussed using kernel‐based
Pierre Duchesne +2 more
wiley +1 more source
Simulating the quantum switch with quantum circuits is computationally hard. [PDF]
Bavaresco J +6 more
europepmc +1 more source
Optimal dividends for a NatCat insurer in the presence of a climate tipping point
Abstract We study optimal dividend strategies for an insurance company facing natural catastrophe claims, anticipating the arrival of a climate tipping point after which the claim intensity and/or the claim size distribution of the underlying risks deteriorates irreversibly.
Hansjörg Albrecher +2 more
wiley +1 more source
Fixed point results for ℑ-Contractions in JS-generalized metric spaces with an application. [PDF]
Iqbal B, Saleem N, Aphane M, Razzaque A.
europepmc +1 more source
Asymptotic properties of cross‐classified sampling designs
Abstract We investigate the family of cross‐classified sampling designs across an arbitrary number of dimensions. We introduce a variance decomposition that enables the derivation of general asymptotic properties for these designs and the development of straightforward and asymptotically unbiased variance estimators.
Jean Rubin, Guillaume Chauvet
wiley +1 more source
Fractional order modeling of prostate cancer with pulsed treatment and the impact of effector cell killing and cell competition. [PDF]
Saber H +5 more
europepmc +1 more source

