Results 91 to 100 of about 23,773 (316)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Evaluation of Port–Hinterland Synergy Level Considering Fixed Asset Allocation and Social Commodity Circulation under the “Dual Circulation” Development Pattern [PDF]

, 2022
Zhaohui Li, Yujin Huang, Fan Yang, Yi Li, Fang Yan, Rui Fu   +5 more
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

The Effect of Transfer Pricing, Profitability, and Fixed Asset Intensity on Tax Aggressiveness with Audit Committee as Moderating Variable

Indonesian Interdisciplinary Journal of Sharia Economics
This study aims to analyze the effect of transfer pricing, profitability, and fixed asset intensity on tax aggressiveness with the audit committee as a moderating variable.
Romita Situmorang, Andang Wirawan Setiabudi   +1 more
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Fixed asset accounting

TRENDS IN THE DEVELOPMENT OF SCIENCE AND EDUCATION, 2021
D.M. Akbasheva, Z.A. Ebzeeva, A.A-S. Abajhanova   +2 more
openaire   +1 more source

PROBLEMS OF ACCOUNTING AND AUDIT OF FIXED ASSETS.

, 2020
Guzalbegim Murodovna Raхimova
openalex   +1 more source

Identification of key problems of the manufacturing industry in the region based on the analysis of fixed assets (on the example of the Vologda oblast)

, 2021
Iryna Demchenko
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

ANALYSIS OF FIXED ASSETS AVAILABILITY IN AGRICULTURAL ORGANIZATIONS OF PENZA REGION

, 2022
E.V. Shirokova, O.V. Lavrina, Ирина Шпагина, I.V. Pavlova   +3 more
openalex   +1 more source