Results 31 to 40 of about 515,541 (307)
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Martingale Optimal Transport and Robust Hedging in Continuous Time [PDF]
The duality between the robust (or equivalently, model independent) hedging of path dependent European options and a martingale optimal transport problem is proved. The financial market is modeled through a risky asset whose price is only assumed to be a
Dolinsky, Yan, Soner, H. Mete
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This research aims to analyze the impact of asset management towards optimality of fixed assets (land and buildings) in the Local Government in Kabupaten Sorong.
Jusmin, Nursalim
doaj +1 more source
Does the Company's Scale, Fixed Asset Intensity and Operating Cash Flow Affect Asset Revaluation?
Fixed assets that are measured using cost may have lost their relevance because they do not reflect the real situation. This study aims to analyze the factors that influence the company to revaluate its fixed assets. The sample of this study consisted of
Rr. Tjahjaning Poerwati +3 more
doaj +1 more source
The decision to Go Public has a great influence in enhancing the company’s performance particularly the company’s financial performance. The purpose of this research is to test whether there are significant differences in the financial performance of PT
Khusnun Fathin +3 more
doaj +1 more source
Procedure Manual for Implementation of GASB 34 by Indiana Local Public Agencies [PDF]
This assistance manual is meant to assist participating governments with certain aspects of the general infrastructure retroactive reporting implementation issues in light of the Governmental Accounting Standards Board Statement No. 34.
Government Fixed Asset Services +1 more
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Penelitian ini bertujuan untuk menganalisis pengaruh kepemilikan manajerial, kepemilikan institusional, pertumbuhan asset, ROA, DPR, net sales, fixed asset ratio dan corporate tax rate terhadap DER pada perusahaan manufaktur yang terdaftar di Bursa Efek ...
Ida Maftukhah
doaj +3 more sources
In an institution of capital assets is one of the very important work that needs to be managed well, both in terms of maximizing the value of benefits and terms of existence that can be used optimally.
Eka Novianti
doaj +1 more source

