Results 131 to 140 of about 692,466 (358)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Recalculation of Fixed Assets in Substantive Testing of Fixed Assets by KAP BCD (Case Study at PT. XYZ)

open access: yesInternational Journal of Business, Economics, and Social Development
Fixed assets are a critical element of financial statements due to their material value and their direct impact on a company’s financial position and performance through depreciation.
Labila Berliana Yasmeen   +1 more
doaj   +1 more source

Peculiarities of fixed assets accounting after January 1, 2015 [PDF]

open access: yes, 2015
Метою статті є дослідження особливості нормативно-правового забезпечення обліку основних засобів, які полягають у подальшій гармонізації їх бухгалтерського обліку з податковим, поступово наближаючись до вимог міжнародних стандартів.
Брік, Світлана Володимирівна   +2 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Accounting and analytical support of the efficiency of fixed assets use in managing the efficiency of business processes of the enterprise

open access: yesФінансово-кредитні системи: перспективи розвитку.
The system of managing the performance of an enterprise in modern conditions is associated with the risks of entrepreneurial activity and directly depends on high-quality accounting and analytical support, which allows making informed management ...
Svitlana Shubina   +4 more
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

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