Results 131 to 140 of about 3,216,879 (306)
, 2008 This program features case studies on cost analysis. Meyer-Mercer Inc. had its supplier and customer base drastically reduced during the recession, yet it was able to survive by accurately analyzing its fixed costs. The second part of the program focuses
core
Hub facility location with fixed costs
Papers in Regional Science, 1992 In thep-hub location model, it is usual to ignore the fixed costs of opening facilities. In contrast, the simple plant location problem includes fixed facility costs and thereby makes thenumber of facilities one of the decision variables. This paper introduces fixed facility costs into a hub location model, thereby making the number of hubs a decision ...
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
SCOPE AND SCALE ECONOMIES FOR MULTI-PRODUCT FARMS: FIRM-LEVEL PANEL DATA ANALYSIS [PDF]
This study used the flexible fixed cost quadratic function to analyze the cost structure of multi-product farms using farm-level panel data. The robustness of estimated parameters are examined using four panel data estimators.
Hossain, Ferdaus, Mafoua, Edouard
core
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
Fixed Exchange Rates, Inflation and Macroeconomic Discipline [PDF]
We use data from Guatemala and Honduras to investigate some implications of the Purchasing Power Parity theory over the long run. In particular, we address two questions.
Sebastian Edwards, Fernando J. Losada
core
IEEE AccessThis study examines the financial impact of energy costs on electric vehicle charging stations by comparing financial models with fixed and variable energy pricing structures. Through an in-depth financial simulation, key metrics such as Internal Rate of
Pathomthat Chiradeja +3 more
doaj +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
VARIABLE AND FIXED COSTS IN COMPANY MANAGEMENT [PDF]
The cost absorbs all the expenses of production for a company at acertain level of the activity. For eliminating the influence of the fixed costs’sabsorbtion and for a better supervision of other causes of digressions, the managerscan apply the method of
Sorin Briciu
core