Results 61 to 70 of about 24,393 (302)

Unilateral mastication‐induced memory deficits linked to disrupted hippocampal cholesterol metabolism in rats

VIEW, EarlyView.
Unilateral mastication, a common oral habit, induces cognitive decline in rats by disrupting hippocampal cholesterol metabolism. It triggers astrocyte hyperplasia, enhances cholesterol synthesis, impairs transport/degradation, and reduces 24‐hydroxycholesterol (24‐OHC), ultimately damaging synaptic function.
Xiaoting Zhai, Yifan Hu, Rongchen Xu, Xinyu Xu, Bowen Ma, Dongzong Huang, Hongchen Liu, Hongbo Li, Yuan Hu, Hua Jiang   +9 more
wiley   +1 more source

A case series on fixed drug eruptions [PDF]

, 2014
A 60 year old male truck driver with a history of recurrent skin boils presented with painful lesions on the glans penis that started a few days prior. A week ago he was treated with co-trimoxazole for skin abscesses on the left leg.
Cascone, John, Newby, Maxwell, Regunath, Hariharan   +2 more
core  

Delayed eruption of permanent dentition and maxillary contraction in patients with cleidocranial dysplasia: review and report of a family [PDF]

, 2018
Introduction. Cleidocranial dysplasia (CCD) is an inherited disease caused by mutations in the RUNX2 gene on chromosome 6p21. This pathology, autosomal dominant or caused by a spontaneous genetic mutation, is present in one in one million individuals ...
Barbato, E., Galluccio, G., Impellizzeri, A., LA MONACA, CAMILLA, Midulla, G., Romeo, U.   +5 more
core   +2 more sources

Clinical Features in the Diagnosis of Drug Reaction With Eosinophilia and Systemic Symptoms: A Retrospective Cohort Study

JEADV Clinical Practice, EarlyView.
Allison Holt, Joseph Ebriani, Bethany Brumbaugh, Mike Westmeijer, Baraa Hijaz, Madeline E. DeWane, Michael Stephens, John Trinidad, Kevin Sheng‐Kai Ma, Steven T. Chen   +9 more
wiley   +1 more source

FaXToR: the hard X‐ray micro‐tomography beamline at the Spanish synchrotron ALBA

Journal of Synchrotron Radiation, EarlyView.
The Spanish synchrotron ALBA has recently inaugurated BL31‐FaXToR, a beamline for hard X‐ray micro‐tomography. The design, performance and scientific program of the beamline are described.FaXToR is the first hard X‐ray imaging beamline built and commissioned at the Spanish synchrotron light source ALBA, and therefore the start of user operation marks ...
Alessandra Patera, Federico Cova, Victorien Bouffetier, Llibert Ribo' Mor, Steven Wohl, Gabriel Vicent Jover Manas, Caori Organista, Josep Nicolas, Alberto Mittone   +8 more
wiley   +1 more source

Toxicodermias por beta-bloqueantes [PDF]

, 2019
La hipertensión arterial es una enfermedad crónica que disminuye la calidad y expectativa de vida, ya que se agrava la morbimortalidad cardiovascular y renal.
Pradillo Heras, Cristina
core  

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania, Barni, Simona, Bottau, Paolo, Caffarelli, Carlo, Caimmi, Davide, Caimmi, Silvia, Cardinale, Fabio, Comberiati, Pasquale, Crisafulli, SEBASTIANO GIUSEPPE, Di Mauro, Dora, Diaferio, Lucia, Duse, Marzia, Franceschini, Fabrizio, Liotti, Lucia, Marseglia, Gianluigi, Mastrorilli, Carla, Mori, Francesca, Paravati, Francesco, Pelosi, Umberto, Saretta, Francesca   +19 more
core   +1 more source

Clinical Characteristics and Risk Factors for Cutaneous Manifestations Associated With Nemolizumab in Atopic Dermatitis: A Multicenter Retrospective Study in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Nemolizumab, an anti‐interleukin‐31 receptor A monoclonal antibody, has been approved in Japan for treating atopic dermatitis (AD)‐associated pruritus. While it is effective for itch control, nemolizumab‐associated cutaneous adverse events have been increasingly recognized, yet their clinical features remain poorly characterized. In this study,
Wataru Sasaki, Ryo Saito, Kenta Suzuki, Daisuke Watanabe, Masako Minami‐Hori, Hirofumi Kamada, Hiroo Amano, Akihiko Uchiyama, Sei‐ichiro Motegi, Machiko Kamura, Kazunari Sugita, Noriko Kubota, Toshifumi Nomura, Maki Ozawa, Toshiya Takahashi, Takashi Yamakita, Kazumitsu Sugiura, Tetsuharu Ikegami, Ken Igawa, Yuka Kimura, Yoko Kataoka, Ryoichi Kamide, Masakazu Takahashi, Akio Tanaka, Mariko Sugawara‐Mikami   +24 more
wiley   +1 more source

Treatment Satisfaction, Efficacy, and Safety of Delgocitinib Ointment Following Switch From Topical Corticosteroids for Trunk and Extremity Rash in Atopic Dermatitis

The Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory disease characterized by recurrent remissions and relapses. Topical anti‐inflammatory steroids are commonly used for treatment, but their long‐term use poses concerns because of potential side effects. Delgocitinib ointment, a Janus kinase inhibitor, has demonstrated efficacy in several clinical
Masatoshi Abe, Atsuyuki Igarashi, Hiroyuki Kitajima, Hiroyuki Toyama, Kenji Kabashima, Hidehisa Saeki   +5 more
wiley   +1 more source

Barriers to Accurate Diagnosis of Infantile Atopic Dermatitis: Insights From a Survey of Pediatricians

The Journal of Dermatology, EarlyView.
ABSTRACT Accurate diagnosis is essential for timely intervention in atopic dermatitis (AD), yet delays in diagnosis remain common. To better understand current clinical practices regarding infantile AD, a questionnaire survey was conducted among Japanese pediatricians working at medical institutions with 19 or fewer beds.
Kiwako Yamamoto‐Hanada, Yasusuke Kawada, Kana Okamoto, Miyuki Matsukawa, Takahiro Tsuchiya, Daisaku Michikami, Yukihiro Ohya   +6 more
wiley   +1 more source