Results 111 to 120 of about 12,179,068 (306)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Almost Consistent Estimation of Panel Probit Models with 'Small' Fixed Effects [PDF]

open access: yes
We propose four different GMM estimators that allow almost consistent estimation of the structural parameters of panel probit models with fixed effects for the case of small T and large N.
Laisney, François, Lechner, Michael
core  

Fixed-effects models on children’s behavior problems (weighted).

open access: yes
Fixed-effects models on children’s behavior problems (weighted).
Wei-Jun Jean Yeung (15448989)   +1 more
core   +1 more source

Tax Incentives and the Intensity of Business Expenditures on Research and Development in Central and Eastern European Countries

open access: yesEconomies
This study assesses the impact of research and development (R&D) tax incentives on the intensity of business R&D expenditure in Central and Eastern European countries and derives policy implications for Ukraine.
Andriy Stavytskyy, Lina Mukhina
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A hyperbolic transformation for a fixed effects logit model [PDF]

open access: yes
In this paper, a simple transformation is proposed for the fixed effects logit model, using which some valid moment conditions including the first-order condition for one of the conditional MLE proposed by Chamberlain (1980) can be generated.
Yoshitsugu Kitazawa
core  

The Impact of Digital Infrastructure and AI Readiness on SME Dynamism

open access: yesFalcons Journal of Advanced Research
This study examined the impact of digital infrastructure and AI readiness on SME dynamism across 153 countries during 2010–2022. Using secondary panel data from the World Bank World Development Indicators, the study constructed a complete-case dataset of
Rabail Zareen, Dr. Areesha Javed
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Semiparametric Fixed-Effects Estimator [PDF]

open access: yes
This paper describes the Stata implementation of Baltagi and Li's (2002) series estimator of partially linear panel data models with fixed effects. After a brief description of the estimator itself, we describe the new command xtsemipar. We then simulate
Fran�ois Libois, Vincenzo Verardi
core  

National income inequality and suicide mortality across 170 countries, 2000–2021: within-country evidence and sensitivity to exposure uncertainty, with implications for health communication

open access: yesFrontiers in Public Health
IntroductionIncome inequality is a distal population exposure, and ecological panel data cannot identify individual-level suicide mechanisms. We examined whether within-country changes in national disposable-income inequality were associated with changes
Guoliang Lu, Xinyun Tang, Xinyun Tang
doaj   +1 more source

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