Results 221 to 230 of about 5,454,839 (350)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Capital adjustment cost and bias in income based dynamic panel models with fixed effects

, 2012
Yoseph Getachew, Keshab Bhattarai, Parantap Basu   +2 more
openalex   +1 more source

The impact of misspecified covariate models on inclusion and omission bias when using fixed effects and full random effects models. [PDF]

J Pharmacokinet Pharmacodyn
Nyberg J, Jonsson EN.
europepmc   +1 more source

Fixed Effects High-Dimensional Profiling Models in Low Information Context. [PDF]

Int J Stat Med Res, 2021
Estes JP, Şentürk D, Kürüm E, Rhee CM, Nguyen DV.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Local economic inequality and mortality: Too little within-unit variation for fixed effects analysis? [PDF]

Scand J Public Health
Elstad JI, Heggebø K, Dahl E.
europepmc   +1 more source

What is the optimal management of potentially resectable stage III-N2 NSCLC? Results of a fixed-effects network meta-analysis and economic modelling. [PDF]

ERJ Open Res, 2023
Evison M, Maconachie R, Mercer T, Daly CH, Welton NJ, Aslam S, West D, Navani N.   +7 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Replication Data for: Fixed Effects and Post-Treatment Bias in Legacy Studies

, 2023
Jonathan Homola, Miguel M. Pereira, Margit Tavits   +2 more
openalex   +1 more source

Inclusion of unexposed clusters improves the precision of fixed effects analysis of stepped-wedge cluster randomized trials with binary and count outcomes. [PDF]

BMC Med Res Methodol
Lee KM, Yang GM, Cheung YB.
europepmc   +1 more source