Results 81 to 90 of about 2,125,440 (312)
The Relationship between Distribution of Income and Health Economy in Iran [PDF]
This paper studies the reciprocal effects of the two important socioeconomic issues, i.e. inequality of income- health through definition of two indices of health in 30 provinces of the country during 1982-2006. Evaluation of the model in the framework
Jamshid Pajuyan, Vida Vaezi
doaj
AI ecosystem pillars and economic growth: Implications for knowledge economy architecture from AI vibrancy subindices [PDF]
Type of the article: Research Article AI is widely regarded by the IMF and the World Bank as a catalyst for growth. AI should be understood as a multidimensional socio-technical system embedded across institutions, industries, and society.
Kalilla Abdullayev +6 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Consistent Estimation of the Fixed Effects Stochastic Frontier Model [PDF]
In this paper we consider a fixed-effects stochastic frontier model. That is, we have panel data, fixed individual (firm) effects, and the usual stochastic frontier analysis (SFA) composed error.
Chen, Yi-Yi; Peter Schmidt; Wang, Hung-Jen +1 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Background: The cross-sectional association between female employment and fertility across developed countries turned from negative to positive during the mid-1980s.
Takashi Oshio
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
This paper investigates the relationship between freight transport, economic growth and environmental degradation (CO2 emissions) experienced by ninety countries over the period 1980-2014.
Listiono Listiono
doaj +1 more source

