Results 41 to 50 of about 7,921,737 (247)

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He   +9 more
wiley   +1 more source

The Effects of Periodontal Laser Therapy on Pain in Adult Patients with Orthodontic Treatment: A Randomized Clinical Trial

open access: yesApplied Sciences, 2022
(1) Background: Pain is the most common complaint of patients with fixed orthodontic treatment, especially when applying and activating the orthodontic device. The effectiveness of low-level laser therapy (LLLT) in reducing pain caused by the orthodontic
Ana-Petra Lazăr   +7 more
doaj   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

open access: yesAdvanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li   +9 more
wiley   +1 more source

Comparative Study of Oral Health-Related Quality of Life (OHRQL) between Different Types of Orthodontic Treatment

open access: yesMedicina, 2021
Background and objectives: Although the main objective of any orthodontic treatment is to correct malocclusion, a range of psychosocial and/or esthetic factors drive patients to undergo orthodontic treatment.
Natalia Zamora-Martínez   +4 more
doaj   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

open access: yesAdvanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao   +7 more
wiley   +1 more source

Extraction Orthodontic Treatment in an Autistic Patient [PDF]

open access: yes, 2017
Autism is a condition that restricts brain development. Early diagnostic criteria are as follows: less responsive to social stimuli, inability to develop natural speaking skills, lack of communication skills, and limited and repetitive behaviors ...
Sinem İnce Bingöl, Ömür Polat Özsoy
core   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

open access: yesAdvanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu   +12 more
wiley   +1 more source

Changes of occlusal plane inclination after orthodontic treatment with four premolars extraction in dento-alveolar bimaxillary protrusion cases

open access: yesPadjadjaran Journal of Dentistry, 2009
The purpose of this study was to find out whether there were changes in occlusal plane inclination after fixed orthodontic treatment of bimaxillary protrusion cases where extraction of four first premolars was needed using the standard Edgewise ...
NR Yuliawati Zenab   +3 more
doaj   +1 more source

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

open access: yesAdvanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang   +15 more
wiley   +1 more source

Knowledge and Practice of Orthodontists Regarding Prevention and Treatment of White Spot Lesions during Fixed Orthodontic Treatment Course in Kurdistan Region-Iraq: A Cross Sectional Study [PDF]

open access: yes, 2020
Objectives: White spot lesions (WSL) are considered the most frequent complication during fixed orthodontic treatment. The aim ofthe present study was to assess the knowledge and practice levels of orthodontic professionals regarding the prevention and ...
Hadi M Ismail   +3 more
core   +2 more sources

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