Results 131 to 140 of about 7,583,170 (338)

Approximate fixed point theorems [PDF]

open access: yesScientific Annals of the A.I.I. Cuza University, 2001
Under some weakenings of the condition of the well-known fixed point theorems of Brouwer, Kakutani and Banach the existence of approximate fixed points turns out to be still guaranteed. Also an approximate fixed point theorem is given for certain nonexpansive maps.
TORRE, ANNA, Tijs S., Brânzei R.
openaire   +6 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

On fractional order model of tumor dynamics with drug interventions under nonlocal fractional derivative

open access: yesResults in Physics, 2021
In our research article, the mathematical model of fractional non-linear cancer dynamical system with the interaction of tumor cells, immune, and drugs reaction systems is taken in ABC derivative sense of fractional order.
Muhammad Arfan   +5 more
doaj  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Fixed points and homotopy fixed points

open access: yesCommentarii Mathematici Helvetici, 1988
Zabrodsky, A., Dror Farjoun, E.
openaire   +2 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy