Results 131 to 140 of about 1,670,188 (219)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Fixed point-based stability analysis of climate and Langevin models. [PDF]

PLoS One
Shah SK, Ahmed WE, Alabdi I, Alahmade A, Aldwoah K, Hassan EI.   +5 more
europepmc   +1 more source

Removing the association of random gene sets and survival time in cancers with positive random bias using fixed-point gene set. [PDF]

Sci Rep, 2023
Maghsoudi M, Aghdam R, Eslahchi C.
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Fixed point results for ℑ-Contractions in JS-generalized metric spaces with an application. [PDF]

PLoS One
Iqbal B, Saleem N, Aphane M, Razzaque A.
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

An algorithm for equilibrium problems with mixed-type fixed point constraints. [PDF]

PLoS One
Guo L, Agwu IK, Ishtiaq U, Alnowibet KA.
europepmc   +1 more source

Fixed Point Attractor Theory Bridges Structure and Function in C. elegans Neuronal Network. [PDF]

Front Neurosci, 2022
Liu J, Lu W, Yuan Y, Xin K, Zhao P, Gu X, Raza A, Huo H, Li Z, Fang T.   +9 more
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Operator means, barycenters, and fixed point equations. [PDF]

Acta Sci Math
Virosztek D.
europepmc   +1 more source