Results 181 to 190 of about 7,821,983 (355)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Functional equation modeling of adaptive operant-control systems via Matkowski fixed point theory. [PDF]

PLoS One
Monica S, Ramesh Kumar D.
europepmc   +1 more source

Solution of differential equations with infinite delay via coupled fixed point. [PDF]

Heliyon, 2022
Mebarki K, Boudaoui A, Shatanawi W, Abodayeh K, Shatnawi TAM.   +4 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Hardware Implementation of a Fixed-Point Decoder for Low-Density Lattice Codes. [PDF]

J Signal Process Syst, 2022
Srivastava R, Gaudet VC, Mitran P.
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Fixed point results for ℑ-Contractions in JS-generalized metric spaces with an application. [PDF]

PLoS One
Iqbal B, Saleem N, Aphane M, Razzaque A.
europepmc   +1 more source

From Moral Fixed Points to Epistemic Fixed Points

, 2018
In a recent paper Terence Cuneo and Russ Shafer-Landau argue that there are moral conceptual truths that are substantive in content, what they called “moral fixed points.” I argue that insofar as we have some reason to postulate moral fixed points, we have equal reason to postulate epistemic fixed points (e.g. the factivity condition).
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

An algorithm for equilibrium problems with mixed-type fixed point constraints. [PDF]

PLoS One
Guo L, Agwu IK, Ishtiaq U, Alnowibet KA.
europepmc   +1 more source