Results 211 to 220 of about 7,583,170 (338)

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

A fixed-point approach for decaying solutions of difference equations. [PDF]

open access: yesPhilos Trans A Math Phys Eng Sci, 2021
Došlá Z, Marini M, Matucci S.
europepmc   +1 more source

Coupled fixed point theorems in partially ordered metric spaces

open access: yesAdvances in Fixed Point Theory, 2019
N. Luong, N. X. Thuan
semanticscholar   +1 more source

Partial Coupled Fixed Points and Coupled Fixed Points [PDF]

open access: yesJournal of Advances in Applied Mathematics, 2016
Peyman Salimi   +2 more
openaire   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

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