Results 241 to 250 of about 5,767,953 (360)
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Posture Detection of Dual-Hemisphere Capsule Robot Based on Magnetic Tracking Effects and ORB-AEKF Algorithm. [PDF]
Liu X, Zhang Y, Wang Q.
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
An algorithm for equilibrium problems with mixed-type fixed point constraints. [PDF]
Guo L, Agwu IK, Ishtiaq U, Alnowibet KA.
europepmc +1 more source
An acceleration technique for fixed point iterative methods [PDF]
openaire +2 more sources
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Autonomous Driving of Trackless Transport Vehicles: A Case Study in Underground Mines. [PDF]
Sun Y, Zhang L, Liu J, Xu Y, Li X.
europepmc +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Robotic Hand-Eye Calibration Method Using Arbitrary Targets Based on Refined Two-Step Registration. [PDF]
Song Z, Sun C, Sun Y, Qi L.
europepmc +1 more source