Results 41 to 50 of about 1,874,752 (330)
Ulam’s Type Stability and Fixed Points Methods [PDF]
1 Department of Mathematics, Pedagogical University, Podchorązych 2, 30-084 Krakow, Poland 2Department of Mathematics, Politehnica University of Timisoara, Piaţa Victoriei No. 2, 300006 Timisoara, Romania 3 Faculty of Applied Mathematics, AGH University of Science and Technology, Mickiewicza 30, 30-059 Krakow, Poland 4 Faculty of Management, University
Janusz Brzdęk+5 more
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Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr+4 more
wiley +1 more source
Fixed Point Method to Analyze Differences between Hipparcos and ICRF2
From 1998, the International Astronomical Union (IAU) adopted a new Celestial Reference System: the International Celestial Reference System (ICRS). The first optical materialization was the Hipparcos catalogue, defining the Hipparcos Celestial Reference
María José Martínez Usó+2 more
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In this paper, a linear system of mixed Volterra-Fredholm integral equations is considered. The problem of existence and uniqueness of its solution is investigated and proved in a complete metric space by using the Banach fixed-point theorem.
Pakhshan M. Hasan+3 more
doaj +1 more source
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten+10 more
wiley +1 more source
Operator means deformed by a fixed point method [PDF]
By means of a fixed point method we discuss the deformation of operator means and multivariate means of positive definite matrices/operators. It is shown that the deformation of an operator mean becomes again an operator mean. The means deformed by the weighted power means are particularly examined.
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Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung+6 more
wiley +1 more source
Characterizations of $\mathcal P$-like continua that do not have the fixed point property [PDF]
We give two characterizations of $\mathcal P$-like continua $X$ that do not have the fixed point property. Both characterizations are stated in terms of sequences of open covers of $X$ that follow fixed-point-free patterns. We use these to characterize planar tree-like continua that do not have the fixed point property in terms of infinite sequences of
arxiv
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher+6 more
wiley +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source