Results 311 to 320 of about 8,443,563 (373)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Microbial and periodontal shifts induced by orthodontic appliances: a comparative clinical study. [PDF]

Acta Odontol Scand
Atasever İşler AA, Erdem A.
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

The Effect of Additive and Multiplicative Cyclic Perturbations on Noise-Induced Tipping Dynamics. [PDF]

Entropy (Basel)
Khovanov IA, Khovanova NA.
europepmc   +1 more source

Non-Hermitian quantum walks uncover dynamical quantum phase transitions under self-normal and biorthogonal bases. [PDF]

Light Sci Appl
Li G, Yuan L.
europepmc   +1 more source

Validation of a Gamified Eye-hand Coordination Tool for Post-stroke Upper Limb Assessment Using Tobii EyeX and Leap Motion: A Pilot Study. [PDF]

Ann Neurosci
Choudhary N, Rawat P.
europepmc   +1 more source

Long-time behaviour and bifurcation analysis of a two-species aggregation-diffusion system on the torus. [PDF]

Calc Var Partial Differ Equ
Carrillo JA, Salmaniw Y.
europepmc   +1 more source

Common Fixed Points for Multimaps in Metric Spaces

, 2010
Nawab Hussain, Esp nola Rafa
openalex   +1 more source

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Fixed points vs. coupled fixed points

Journal of Fixed Point Theory and Applications, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
A. Petruşel
semanticscholar   +3 more sources

Provable Fixed Points

Mathematical Logic Quarterly, 1988
The paper establishes some general conditions under wich a formula A(p) has only provable fixed points in Guaspari-Solovay modal logic of provability R. This result is used to give another proof of Parikh's theorem: For each natural number \(k\geq 1\) there is an arithmetical sentence A, provable in PA, such that \(\square^ kA\) has a much shorter ...
de Jongh, Dick, Montagna, Franco
openaire   +2 more sources