Results 71 to 80 of about 4,586,045 (294)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fixed point theorems via Nash Equilibria [PDF]
In this note we show that the fixed points of a continuous function (or of an upper semi-continuous correspondence, with non-empty and convex values) can be attained as Nash Equilibria of a game with finitely many players.
Juan Pablo Torres-Martínez
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2017 The Fixperts film archive hosts the documentation aspect of design based Fixperts projects from participants all around the world. It is managed though Youtube and disseminated through a dedicated online platform on the FixEd website.
Charny, Daniel, FixEd
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Fixed Points in Functional Inequalities
Journal of Inequalities and Applications, 2008 Using fixed point methods, we prove the generalized Hyers-Ulam stability of the following functional inequalities and in the spirit of Th. M. Rassias stability approach.
Park Choonkil
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fixed Points Results in G-Metric Spaces
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2019 In this paper, the concept of contraction mapping on a -metric space is extended with a consideration on local contraction. As a result, two fixed point theorems were proved for contraction on a closed ball in a complete -metric space.
Salwa Salman Abed, Anaam Neamah Faraj
doaj +1 more source
Abstract Fixed-Point Theorems and Fixed-Point Iterative Schemes
Symmetry, 2022 Mathematical methods are extensively used in dealing with simulation and approximation problems related to computer science, engineering, physics, and many others [...]
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source