Results 91 to 100 of about 1,167,438 (285)

A prospective clinical evaluation of fixed retainer failures

open access: yes, 2017
Objective: The aim of this prospective study was to evaluate the failure rate of fixed lingual retainers and to determine the distribution of these failures over a 6-month period.
Mehmet Akın   +3 more
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Fixperts films archive

open access: yes, 2017
The Fixperts film archive hosts the documentation aspect of design based Fixperts projects from participants all around the world. It is managed though Youtube and disseminated through a dedicated online platform on the FixEd website.
Charny, Daniel, FixEd
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Veneer-Based Fixed Lingual Retainer: In Vitro Evaluation of Shear Bond Strength and Adhesive Remnant Index

open access: yes
Objectives Orthodontic relapse, the tendency of teeth to return toward their pre-treatment positions, remains a major challenge and has led to widespread use of fixed lingual retainers to preserve stability.
Diva Lugassy   +4 more
core   +1 more source

Orthodontic Retention Protocols: Evaluating the Effectiveness of Different Retention Protocols in Maintaining Post-Treatment Tooth Alignment

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To evaluate the effectiveness of various orthodontic retention protocols, including removable retainers, fixed retainers, and a combination of both.
Snigdha Pattanaik   +4 more
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Finite Element Analysis of Fixed Orthodontic Retainers

open access: yesBioengineering
The efficacy of retainers is a pivotal concern in orthodontic care. This study examined the biomechanical behaviour of retainers, particularly the influence of retainer stiffness and tooth resilience on force transmission and stress distribution. To do this, a finite element model was created of the lower jaw from the left to the right canine with a ...
Sebastian Hetzler   +5 more
openaire   +3 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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