Results 151 to 160 of about 338,471 (290)

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

#101 Comportamento tribocorrosivo do TiAlV: efeito do flúor e da amálgama no desgaste desta liga [PDF]

, 2022
Beatriz Ferreira Fernandes, Mariana Cruz, Gonçalo Xavier de Almeida Garrett, Óscar Carvalho, Joana Marques, Craig Murdoch   +5 more
openalex   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Evaluación in vitro de la resistencia compresiva de un sellante resinoso fluorado pre y post liberación de flúor [PDF]

, 2012
Carolina González Vergara, Sergio Uribe
openalex   +1 more source

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

Advanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang, Lasse Riediger, Qi Rao, Xun Xu, Yan Nie, Yiduo Zhou, Junyao Zhang, Peng Tang, Weiwei Wang, Frank Tacke, Adrien Guillot, Ludovic Vallier, Irene Talon, Wenzhong Li, Yi‐An Yang, Rainer Haag, Nan Ma   +16 more
wiley   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Desempenhos produtivo e reprodutivo da progênie de porcas alimentadas com diferentes fontes de fósforo

Boletim de Indústria Animal, 2014
Os efeitos de diferentes fontes de fósforo sobre a progênie de porcas foram estudados em dois experimentos durante 2,7 anos, ou seja 970 dias. No primeiro, foram utilizadas 45 marrãs Landrace (15 por tratamento), após acasalamento com machos Large ...
Hacy Pinto Barbosa, Nelson Mores, Elias Tadeu Filho, Antônio Lourenço Guidoni   +3 more
doaj  

ELIMINACIÓN DE FLÚOR EN AGUA POTABLE UTILIZANDO ZEOLITA NATURAL (CLINOPTILOLITA) [PDF]

, 2013
Agustín Cota, Manuel Balcázar Meza, María Virginia Fernández Ramírez, Julio César Morales Munguía, Jaime Varela Salazar   +4 more
openalex   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Efeito de diferentes fontes de fósforo na dieta sobre as características dos ossos de porcas e suas proles

Pesquisa Veterinária Brasileira, 1999
A limitação principal do uso de fosfatos naturais na alimentação de suínos é a presença de flúor que pode ser tóxico quando ingerido por longos períodos.
Morés Nelson, Barbosa Hacy Pinto, Barioni Jr Waldomiro   +2 more
doaj