Results 181 to 190 of about 328,534 (192)

The IRE1 α -XBP1s-NF κ B axis controls cell survival and epithelial differentiation under osmotic stress through arachidonic acid metabolism activation. [PDF]

Cell Stress
Parra LG, Casali CI, Sendyk DE, Salafia AF, Flor SA, Lucangioli SE, Tome MDCF.   +6 more
europepmc   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Mature tertiary lymphoid structures in pilonidal sinus disease. [PDF]

JID Innov
Gupta R, Suresh RR, Roberson JL, Lee M, Maguire LH, Fang V.   +5 more
europepmc   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Ca₁₃Mab-17, a Novel Anti-Cadherin-13 Monoclonal Antibody for Versatile Applications. [PDF]

Antibodies (Basel)
Shimizu K, Suzuki H, Kaneko MK, Kato Y.
europepmc   +1 more source

Comparative Analysis of Glycan Composition in Therapeutic Antibodies via Glycan Profiling and Intact Mass Analysis. [PDF]

Molecules
Chun YS, Lee JB, Seomun S, Park S, Na JH, Ko BJ.   +5 more
europepmc   +1 more source

The PDE5 inhibitor vardenafil enhances glutamatergic transmission through amyloid-beta and cellular prion protein. [PDF]

Neurotherapeutics
Kafi MAA, Passalacqua M, Villa V, Thellung S, Corsaro A, Grimaldi R, Spatola E, Florio T, Baldelli P, Ricciarelli R.   +9 more
europepmc   +1 more source

Cardiovascular β-Adrenergic Receptor Distribution and Function: Influence of Species, Sex, Age, and Tissue. [PDF]

Compr Physiol
Elsaid B, Kopaliani I, Zatschler B, Seif A, Speier S, Deussen A.   +5 more
europepmc   +1 more source

Protocol to study murine ovarian elasticity and composition in situ by integrating quantitative micro-elastography with light microscopy. [PDF]

STAR Protoc
Jaeschke A, Hepburn MS, Mowla A, Eckert H, Kennedy BF, Chan CJ.   +5 more
europepmc   +1 more source

StarD5 Regulates Cholesterol Homeostasis to Promote Colorectal Cancer Progression and the Cancer Stem Cell Phenotype. [PDF]

Mol Cancer Res
Sharon C, Rodriguez-Agudo D, Boothello RS, Haneefa SM, Pandak WM, Gil G, Patel BB.   +6 more
europepmc   +1 more source