Using skin biopsies to measure target occupancy of anti-fibrotic molecules: assay development and application for zampilimab in a primate model of chronic kidney disease and in healthy human volunteers. [PDF]
Huang L +6 more
europepmc +1 more source
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij +8 more
wiley +1 more source
Protocol to study murine ovarian elasticity and composition in situ by integrating quantitative micro-elastography with light microscopy. [PDF]
Jaeschke A +5 more
europepmc +1 more source
ODONTOLOGÍA: Lo que debe saber el médico sobre la profilaxis de la caries dental [PDF]
Ast, David B.
core
A tunable bifunctional surface is developed by combining Fc‐binding peptides and RGD motifs to present oriented antibodies alongside integrin‐mediated signaling. The platform selectively captures endothelial colony‐forming cells while promoting their adhesion and proliferation.
Hugo A. Level +5 more
wiley +1 more source
Avaliação in vitro da liberação e da recarga de flúor em cimentos de ionômero de vidro
OBJETIVO: Este estudo avaliou a absorção de íons flúor em cimentos de ionômero de vidro de manipulação mecânica e manual, por uma única aplicação tópica de flúor.
Evelyn Lopez Leite +4 more
doaj
Spatiotemporal analysis of cell division during symbiotic root nodule development in the model legume Medicago truncatula. [PDF]
Wickens G, Greensmith E, Schiessl K.
europepmc +1 more source
Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López +5 more
wiley +1 more source
Live-cell 3D-SIM of Rift Valley fever virus NSs filaments reveals a polygon web architecture. [PDF]
Dunlop JI +4 more
europepmc +1 more source
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li +9 more
wiley +1 more source

