Results 211 to 220 of about 338,471 (290)
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li+8 more
wiley +1 more source
Pre-formation loading of extracellular vesicles with exogenous molecules using photoporation. [PDF]
Ramon J+15 more
europepmc +1 more source
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu+9 more
wiley +1 more source
Inverse Design of Multi-Wavelength Achromatic Metalens Integrated On-Chip with Planar Waveguide. [PDF]
Podobrii M, Barulina E, Barulin A.
europepmc +1 more source
Concentração de íons flúor em águas minerais envasadas no Rio Grande do Sul
Alexandre Emidio Ribeiro da Silva+5 more
openalex +2 more sources
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao+20 more
wiley +1 more source
Quantifying small GTPase activation status using a novel fluorescence HPLC-based assay. [PDF]
Araki M+4 more
europepmc +1 more source
Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang+12 more
wiley +1 more source