Results 231 to 240 of about 316,716 (242)

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

open access: yesAdvanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang   +8 more
wiley   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

open access: yesAdvanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu   +15 more
wiley   +1 more source

Mast Cell Association with the Microenvironment of a Phosphaturic Mesenchymal Tumour Secreting Fibroblast Growth Factor 23. [PDF]

open access: yesMed Sci (Basel)
Kostin A   +12 more
europepmc   +1 more source

The antifungal mechanism of EntV-derived peptides is associated with a reduction in extracellular vesicle release. [PDF]

open access: yesPLoS Pathog
Buda De Cesare G   +9 more
europepmc   +1 more source

MMP-cleavable linker platform for tumour-responsive homo- and heterobivalent antibody-drug conjugates. [PDF]

open access: yesChem Sci
Counsell AJ   +8 more
europepmc   +1 more source

Phenotypic profiling of small molecules using cell painting assay in HCT116 colorectal cancer cells. [PDF]

open access: yesPLoS One
Lavrinenko V   +5 more
europepmc   +1 more source

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