Results 61 to 70 of about 68,417 (200)

Harnessing Natural Killer Cells: From Neuroimmunology to Novel Therapies for Central Nervous System Diseases

open access: yesMedComm, Volume 7, Issue 10, October 2026.
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley   +1 more source

Acute flaccid paralysis by enterovirus D68 infection: first Italian description on adult patient and role of electrophysiology [PDF]

open access: yes, 2017
A Peruvian woman was admitted to the Emergency Department, due to an acute flaccid paralysis of the upper limbs that progressively involved also lower limbs and respiratory muscles.
Federica Romanzi   +8 more
core   +1 more source

Clinical Practice of Single‐Molecule Real‐Time Sequencing in the Diagnosis of Spinal Muscular Atrophy

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 10, October 2026.
SMRT sequencing accurately resolves SMN1 and SMN2 copy numbers, revealing an SMA carrier frequency of 2.33% and gene distribution patterns. Integrated with case analysis, it provides critical insights for clinical diagnosis and genetic counseling.
Hua Wei   +6 more
wiley   +1 more source

Pediatric Guillain‐Barré Syndrome Post Organ Transplant: Acute and Chronic Complication Requiring High Index of Suspicion

open access: yesPediatric Transplantation, Volume 30, Issue 10, October 2026.
ABSTRACT Background Guillain‐Barré syndrome (GBS) is an acute, immune‐mediated polyradiculoneuropathy most often triggered by infections such as Campylobacter jejuni, Epstein–Barr virus (EBV), or cytomegalovirus (CMV). Although transplant‐associated GBS is recognized in adults, it remains rare in pediatric recipients, and distinguishing immune‐mediated
Liora Rabizadeh, Paola Pergami
wiley   +1 more source

Clinical and diagnostic characteristics of patients with suspected polyneuropathy [PDF]

open access: yesСаратовский научно-медицинский журнал, 2013
Objective: to study the causes and clinical manifestations of disease in children referred for hospitalization in children infectious diseases hospital in Saratov with a diagnosis of «acute flaccid paralysis».
Mikhailova Е.V.   +4 more
doaj  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1903-1918, September 2026.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Surveillance of acute flaccid paralysis in Hong Kong: 1997 to 2002 [PDF]

open access: yes, 2005
Objectives. To describe the characteristics of patients reported with acute flaccid paralysis between 1997 and 2002, and to evaluate the performance of the acute flaccid paralysis surveillance system using indicators recommended by the World Health ...
Lau, YL   +6 more
core  

Acute flaccid paralysis: An approach to diagnosis

open access: yes, 2017
Acute flaccid paralysis (AFP) is a common presentation to the emergency department and can present with paralysis of single to several limbs. Here is a case with AFP presented to highlight the approach to diagnosis.
A Yadav   +5 more
core   +1 more source

Evaluation of Health Care Workers’ Knowledge about Acute Flaccid Paralysis in Najaf City/Iraq

open access: yesمجلة الكوفة الطبية
Background: Acute Flaccid Paralysis (AFP) is a severe clinical symptom that could have a variety of different causes. Acute flaccid paralysis (AFP) is a clinical symptom characterized by the sudden onset of weakness or paralysis and decreased muscle ...
Hala J. Jasim, Naja H. Hassan
doaj   +1 more source

Penile intracavernosal injection of succinylcholine for laryngospasm management during hypospadias repair

open access: yesUroPrecision, Volume 4, Issue 3, Page 189-193, September 2026.
Abstract Background Laryngospasm is a serious anesthetic complication that can lead to acute airway obstruction and hypoxemia. Standard management involves deepening anesthesia and administering succinylcholine intravenously (IV) or intramuscularly (IM). However, if IV access is lost or IM drug delivery is too slow, alternative routes are required.
Diego R. Álvarez Vega   +6 more
wiley   +1 more source

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